Literature DB >> 6360054

Beta cell function in siblings of diabetic children and HLA type.

E Schober, G Schernthaner, H Frisch, J Bieber, W Mayr.   

Abstract

Beta cell function was tested in HLA-DR typed siblings of insulin dependent diabetic children. HLA identical siblings showed an increased insulin response compared with controls and HLA nonidentical siblings. This beta cell hyperactivity may be an early carbohydrate intolerance or a genetically determined increase in beta cell metabolism.

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Year:  1983        PMID： 6360054      PMCID： PMC1628383          DOI： 10.1136/adc.58.11.923

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  5 in total

1.  Muscle extracellular membrane immunofluorescence and HLA as possible markers of prediabetes.

Authors:  J Barbosa; R A Cohen; B Chavers; A F Michael; M Steffes; B Hoogwerf; E Szalapski; M Mauer
Journal:  Lancet       Date:  1980-08-16       Impact factor: 79.321

2.  Complement-fixing islet-cell antibodies before and after onset of insulin-dependent diabetes.

Authors:  J Ilonen; A Mustonen; H K Akerblom; N P Huttunen
Journal:  Lancet       Date:  1980-10-11       Impact factor: 79.321

3.  Evidence for a long prediabetic period in type I (insulin-dependent) diabetes mellitus.

Authors:  A N Gorsuch; K M Spencer; J Lister; J M McNally; B M Dean; G F Bottazzo; A G Cudworth
Journal:  Lancet       Date:  1981 Dec 19-26       Impact factor: 79.321

4.  Ten-year prognosis of impaired glucose tolerance in siblings of patients with insulin-dependent diabetes.

Authors:  A L Rosenbloom; S S Hunt; E K Rosenbloom; N K Maclaren
Journal:  Diabetes       Date:  1982-05       Impact factor: 9.461

5.  Beta-cell dysfunction in nondiabetic HLA identical siblings of insulin-dependent diabetics.

Authors:  P H Hollander; C M Asplin; D Kniaz; J A Hansen; J P Palmer
Journal:  Diabetes       Date:  1982-02       Impact factor: 9.461
  5 in total
  2 in total

1.  Glucose-induced insulin response and insulin sensitivity is not related to HLA-type but to age in young siblings of type 1 (insulin-dependent) diabetic patients.

Authors:  F Lindgren; G Dahlquist; S Efendic; E Möller; B Persson; B Thalme; M L Olsson
Journal:  Diabetologia       Date:  1987-09       Impact factor: 10.122

Review 2.  Cause or effect? A review of clinical data demonstrating beta cell dysfunction prior to the clinical onset of type 1 diabetes.

Authors:  Emily K Sims; Linda A DiMeglio
Journal:  Mol Metab       Date:  2019-09       Impact factor: 7.422
  2 in total

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