Literature DB >> 6358335

The effect of topical insulin on infected cutaneous ulcerations in diabetic and nondiabetic mice.

S R Hanam, C E Singleton, W Rudek.   

Abstract

A study to determine the efficacy of topical insulin on wound healing in 41 diabetic and nondiabetic mice was performed. The results showed that treatment regimens that included topical insulin provided better rates of wound healing than treatment regimens in which only base preparations or controls were used. Healing rates were improved in both diabetic and nondiabetic mice.

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Year:  1983        PMID： 6358335

Source DB:  PubMed          Journal:  J Foot Surg        ISSN： 0449-2544


  9 in total

Review 1.  Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy".

Authors:  Christy L Scimeca; Manish Bharara; Timothy K Fisher; Heather Kimbriel; Joseph L Mills; David G Armstrong
Journal:  J Diabetes Sci Technol       Date:  2010-07-01

Review 2.  A role for topical insulin in the management problematic surgical wounds.

Authors:  J M Wilson; R Baines; E D Babu; C J Kelley
Journal:  Ann R Coll Surg Engl       Date:  2008-03       Impact factor: 1.891

3.  Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial.

Authors:  Maria H M Lima; Andréa M Caricilli; Lélia L de Abreu; Eliana P Araújo; Fabiana F Pelegrinelli; Ana C P Thirone; Daniela M Tsukumo; Ana Flávia M Pessoa; Marinilce F dos Santos; Maria A de Moraes; José B C Carvalheira; Lício A Velloso; Mario J A Saad
Journal:  PLoS One       Date:  2012-05-25       Impact factor: 3.240

4.  Effects of topical insulin on second-intention wound healing in the red-eared slider turtle (Trachemys scripta elegans) - a controlled study.

Authors:  Joao Negrini; Elena Mozos; Alejandro Escamilla; José Pérez; Rosario Lucena; Rafael Guerra; Pedro J Ginel
Journal:  BMC Vet Res       Date:  2017-06-06       Impact factor: 2.741

5.  Peptidic inhibitors of insulin-degrading enzyme with potential for dermatological applications discovered via phage display.

Authors:  Caitlin N Suire; Sarah Nainar; Michael Fazio; Adam G Kreutzer; Tara Paymozd-Yazdi; Caitlyn L Topper; Caroline R Thompson; Malcolm A Leissring
Journal:  PLoS One       Date:  2018-02-15       Impact factor: 3.240

6.  Cell and molecular mechanisms of keratinocyte function stimulated by insulin during wound healing.

Authors:  Yan Liu; Melissa Petreaca; Min Yao; Manuela Martins-Green
Journal:  BMC Cell Biol       Date:  2009-01-12       Impact factor: 4.241

7.  Limited Treatment Options for Diabetic Wounds: Barriers to Clinical Translation Despite Therapeutic Success in Murine Models.

Authors:  May Barakat; Luisa A DiPietro; Lin Chen
Journal:  Adv Wound Care (New Rochelle)       Date:  2020-12-18       Impact factor: 4.947

8.  Cell and molecular mechanisms of insulin-induced angiogenesis.

Authors:  Yan Liu; Melissa Petreaca; Manuela Martins-Green
Journal:  J Cell Mol Med       Date:  2009 Nov-Dec       Impact factor: 5.310

9.  Insulin regulates multiple signaling pathways leading to monocyte/macrophage chemotaxis into the wound tissue.

Authors:  Yan Liu; Sandeep Dhall; Anthony Castro; Alex Chan; Raquelle Alamat; Manuela Martins-Green
Journal:  Biol Open       Date:  2018-01-17       Impact factor: 2.422
  9 in total

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