Literature DB >> 6355856

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells.

P I Schrier, R Bernards, R T Vaessen, A Houweling, A J van der Eb.   

Abstract

Rat cells transformed by the highly oncogenic adenovirus 12 lack at least two cellular proteins which are present in cells transformed by the non-oncogenic adenovirus 5 and in untransformed cells. One protein has been identified as the heavy chain of the rat class I major histocompatibility complex. This finding may explain the difference in oncogenicity between adenoviral species.

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Year:  1983        PMID： 6355856     DOI： 10.1038/305771a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  188 in total

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