Literature DB >> 6354900

Immunohistochemical identification of lysozyme in pseudopyloric gland metaplasia in Crohn's disease.

K Geboes, J J Van den Oord, P Rutgeerts, V J Desmet, G Vantrappen.   

Abstract

Using an immunoperoxidase technique lysozyme (LZM) was identified in the ileum of patients with Crohn's disease in inflammatory cells of the lamina propria, in Paneth cells and in pseudopyloric gland metaplasia. These observations demonstrate a further analogy of pseudopyloric gland metaplasia with true pyloric glands, and may offer an additional explanation for the raised concentration of serum-LZM in patients with Crohn's disease.

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Year:  1983        PMID: 6354900

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  6 in total

1.  Is pyloric gland metaplasia in ileal pouch biopsies a marker for Crohn's disease?

Authors:  Shuchi Agarwal; Arthur F Stucchi; Kleanthis Dendrinos; Sandra Cerda; Michael J O'Brien; James M Becker; Timothy Heeren; Francis A Farraye
Journal:  Dig Dis Sci       Date:  2013-03-30       Impact factor: 3.199

2.  Broad-spectrum antimicrobial activity of human intestinal defensin 5.

Authors:  E M Porter; E van Dam; E V Valore; T Ganz
Journal:  Infect Immun       Date:  1997-06       Impact factor: 3.441

3.  Localization of human intestinal defensin 5 in Paneth cell granules.

Authors:  E M Porter; L Liu; A Oren; P A Anton; T Ganz
Journal:  Infect Immun       Date:  1997-06       Impact factor: 3.441

4.  Fecal lysozyme in assessment of disease activity in inflammatory bowel disease.

Authors:  A van der Sluys Veer; J Brouwer; I Biemond; G E Bohbouth; H W Verspaget; C B Lamers
Journal:  Dig Dis Sci       Date:  1998-03       Impact factor: 3.199

Review 5.  Cellular Plasticity, Reprogramming, and Regeneration: Metaplasia in the Stomach and Beyond.

Authors:  James R Goldenring; Jason C Mills
Journal:  Gastroenterology       Date:  2021-10-30       Impact factor: 22.682

6.  Microscopic features of small bowel mucosa of patients with Crohn's disease.

Authors:  Yun Cui; Shi-Yuan Lu; Jie Xu; Yan-Shen Peng; Qi Miao; Xiao-Qing Wang; Xiao-Yu Chen; Zhi-Hua Ran
Journal:  BMC Gastroenterol       Date:  2019-12-30       Impact factor: 3.067

  6 in total

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