Literature DB >> 6353562

Evaluation of the inbred mouse as a model for experimental Treponema pallidum infection.

J D Folds, A S Rauchbach, E Shores, J M Saunders.   

Abstract

Mice of several inbred strains were studied for responses to Treponema pallidum (Nichols). Mice were injected with viable treponemes and observed daily for the presence of lesions or signs of illness. Although none of the mice developed detectable lesions, they did develop specific anti-T. pallidum antibodies that were observed as early as 21 days after inoculation with viable T. pallidum. The antibodies were detected by an enzyme-linked immunosorbent assay and by passive haemagglutination.

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Year:  1983        PMID： 6353562     DOI： 10.1111/j.1365-3083.1983.tb00858.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  4 in total

1.  Experimental infection of inbred guinea pigs with Treponema pallidum: development of lesions and formation of antibodies.

Authors:  C S Pavia; C J Niederbuhl
Journal:  Genitourin Med       Date:  1985-04

2.  Humoral response of the mouse to Treponema pallidum.

Authors:  J M Saunders; J D Folds
Journal:  Genitourin Med       Date:  1985-08

3.  Characterization of Treponema pallidum Dissemination in C57BL/6 Mice.

Authors:  Simin Lu; Kang Zheng; Jianye Wang; Man Xu; Yafeng Xie; Shuai Yuan; Chuan Wang; Yimou Wu
Journal:  Front Immunol       Date:  2021-01-08       Impact factor: 7.561

4.  MyD88 deficiency markedly worsens tissue inflammation and bacterial clearance in mice infected with Treponema pallidum, the agent of syphilis.

Authors:  Adam C Silver; Dana W Dunne; Caroline J Zeiss; Linda K Bockenstedt; Justin D Radolf; Juan C Salazar; Erol Fikrig
Journal:  PLoS One       Date:  2013-08-05       Impact factor: 3.240
  4 in total

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