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Literature DB >> 6352957

Measurement of repair patch size by quantitation of nucleotides excised during DNA repair in vivo.

Abstract

Escherichia coli uvr- cells, prelabeled in their DNA, were infected with phage T4 denV+ or T4 denV- under conditions that preclude phage-mediated degradation of the bacterial chromosome. Measurement of the distribution of acid-soluble radioactivity between pyrimidine dimers and nondimer nucleotides in cell extracts yielded calculated estimates of the average size of excision repair tracts that are in good agreement with the size of repair patches determined by others using direct measurement of repair synthesis.

Entities: Chemical Species

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Year: 1983 PMID： 6352957 PMCID： PMC255269

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

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References

17 in total

1. The production of undegraded cytosine-containing DNA by bacteriophage T4 in the absence of dCTPase and endonucleases II and IV, and its effects on T4-directed protein synthesis.

Authors: E Kutter; A Beug; R Sluss; L Jensen; D Bradley
Journal: J Mol Biol Date: 1975-12-25 Impact factor: 5.469

2. Isolation of bacteriophage T4 mutants defective in the ability to degrade host deoxyribonucleic acid.

Authors: H R Warner; P Snustad; S E Jorgensen; J F Koerner
Journal: J Virol Date: 1970-06 Impact factor: 5.103

3. Excision-repair in mutants of Escherichia coli deficient in DNA polymerase I and/or its associated 5' leads to 3' exonuclease.

Authors: P Cooper
Journal: Mol Gen Genet Date: 1977-01-07

4. Enzymes involved in thymine dimer excision in bacteriophage T4-infected Escherichia coli.

Authors: G Pawl; R Taylor; K Minton; E C Friedberg
Journal: J Mol Biol Date: 1976-11 Impact factor: 5.469

5. Physical association of pyrimidine dimer DNA glycosylase and apurinic/apyrimidinic DNA endonuclease essential for repair of ultraviolet-damaged DNA.

Authors: Y Nakabeppu; M Sekiguchi
Journal: Proc Natl Acad Sci U S A Date: 1981-05 Impact factor: 11.205

Measurement of repair patch size by quantitation of nucleotides excised during DNA repair in vivo.

1. The production of undegraded cytosine-containing DNA by bacteriophage T4 in the absence of dCTPase and endonucleases II and IV, and its effects on T4-directed protein synthesis.

2. Isolation of bacteriophage T4 mutants defective in the ability to degrade host deoxyribonucleic acid.

3. Excision-repair in mutants of Escherichia coli deficient in DNA polymerase I and/or its associated 5' leads to 3' exonuclease.

4. Enzymes involved in thymine dimer excision in bacteriophage T4-infected Escherichia coli.

5. Physical association of pyrimidine dimer DNA glycosylase and apurinic/apyrimidinic DNA endonuclease essential for repair of ultraviolet-damaged DNA.

6. den V gene of bacteriophage T4 determines a DNA glycosylase specific for pyrimidine dimers in DNA.

7. Analysis of resynthesis tracts in repaired Escherichia coli deoxyribonucleic acid.

8. DNA N-glycosylases and UV repair.

9. A pyrimidine dimer-DNA glycosylase activity associated with the v gene product of bacterophage T4.

10. Cleavage of pyrimidine dimers in specific DNA sequences by a pyrimidine dimer DNA-glycosylase of M. luteus.