Literature DB >> 6352721

Determination of N tau-methylhistamine in urine by gas chromatography using nitrogen-phosphorus detection.

J J Keyzer, B G Wolthers, H Breukelman, W van der Slik.   

Abstract

The determination of N tau-methylhistamine in urine, using gas chromatography with nitrogen-phosphorus detection and the homologue N tau-ethylhistamine as internal standard, is described. A comparison between the present method and a previously described stable isotope dilution mass fragmentographic method resulted in a regression line of Y = 0.023 + 0.944X mumol/l with a correlation coefficient of 0.996. The 24-h excretions of 35 normal adults on a free diet ranged from 0.4 to 1.8 mumol. Patients with mastocytosis, chronic myelocytic leukemia, anaphylactic reactions and a patient after bronchial provocation showed above normal values.

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Year:  1983        PMID: 6352721

Source DB:  PubMed          Journal:  J Chromatogr


  7 in total

1.  Measurement of urinary N tau-methylhistamine excretion: correlation of a newly developed radioimmunoassay (RIA) with gas chromatography mass spectrometry (GCMS).

Authors:  E Oosting; J J Keyzer
Journal:  Agents Actions       Date:  1991-05

Review 2.  Aspects of histamine metabolism.

Authors:  J P Green; G D Prell; J K Khandelwal; P Blandina
Journal:  Agents Actions       Date:  1987-10

3.  Measurement of N tau-methylhistamine concentrations in plasma and urine as a parameter for histamine release during anaphylactoid reactions.

Authors:  J J Keyzer; H Breukelman; B G Wolthers; F J Richardson; J G de Monchy
Journal:  Agents Actions       Date:  1985-04

4.  Influence of decontamination of the digestive tract on the urinary excretion of histamine and some of its metabolites.

Authors:  J J Keyzer; H K van Saene; G A van den Berg; B G Wolthers
Journal:  Agents Actions       Date:  1984-10

5.  Nocturnal airflow obstruction, histamine, and the autonomic central nervous system in children with allergic asthma.

Authors:  W M van Aalderen; D S Postma; G H Koëter; K Knol
Journal:  Thorax       Date:  1991-05       Impact factor: 9.139

6.  Histamine in late asthmatic reactions following house-dust mite inhalation.

Authors:  J G de Monchy; J J Keyzer; H F Kauffman; F Beaumont; K de Vries
Journal:  Agents Actions       Date:  1985-04

7.  Urinary excretion of histamine and some of its metabolites in man: influence of the diet.

Authors:  J J Keyzer; H Breukelman; B G Wolthers; M van den Heuvel; N Kromme; W C Berg
Journal:  Agents Actions       Date:  1984-10
  7 in total

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