Literature DB >> 6352645

A preliminary pharmacokinetic study of ceftazidime in premature, new born and small infants.

J G Prinsloo, S D Delport, J Moncrieff, A M Paton.   

Abstract

Fifty neonates and infants with suspected or proven bacterial infection were given 30 mg/kg of ceftazidime as a single intravenous dose to investigate the pharmacokinetics of ceftazidime. The mean serum half-lives for babies aged less than 2 months was 4.18 +/- 1.60 h and for those aged 2 to 12 months 2.00 +/- 0.64 h. Dose bands of 25 to 50 mg/kg/day for those less than two months and 50-100 mg/kg/day for those aged 2 to 12 months are recommended for the treatment of suitable bacterial infections.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6352645     DOI: 10.1093/jac/12.suppl_a.361

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  7 in total

Review 1.  [Ceftazidime in the treatment of pediatric infections--a review].

Authors:  D Adam; R Tolxdorff-Neutzling
Journal:  Infection       Date:  1987       Impact factor: 3.553

Review 2.  Clinical pharmacokinetics of antibacterial drugs in neonates.

Authors:  C M Paap; M C Nahata
Journal:  Clin Pharmacokinet       Date:  1990-10       Impact factor: 6.447

3.  Ceftazidime pharmacokinetics in preterm infants: effect of postnatal age and postnatal exposure to indomethacin.

Authors:  J N van den Anker; W C Hop; R C Schoemaker; B J van der Heijden; H J Neijens; R de Groot
Journal:  Br J Clin Pharmacol       Date:  1995-11       Impact factor: 4.335

Review 4.  Commonly used antibacterial and antifungal agents for hospitalised paediatric patients: implications for therapy with an emphasis on clinical pharmacokinetics.

Authors:  J Singh; B Burr; D Stringham; A Arrieta
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

5.  Population Pharmacokinetics and Dosing Optimization of Ceftazidime in Infants.

Authors:  Zhong-Ren Shi; Xing-Kai Chen; Li-Yuan Tian; Ya-Kun Wang; Gu-Ying Zhang; Lei Dong; Totsapol Jirasomprasert; Evelyne Jacqz-Aigrain; Wei Zhao
Journal:  Antimicrob Agents Chemother       Date:  2018-03-27       Impact factor: 5.191

6.  Once-daily versus twice-daily administration of ceftazidime in the preterm infant.

Authors:  J N van den Anker; R C Schoemaker; B J van der Heijden; H M Broerse; H J Neijens; R de Groot
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

Review 7.  Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  D M Richards; R N Brogden
Journal:  Drugs       Date:  1985-02       Impact factor: 9.546

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.