Literature DB >> 6351622

Hanganutziu-Deicher heterophile antigen in human retinoblastoma cells.

Y Ohashi, T Sasabe, T Nishida, Y Nishi, H Higashi.   

Abstract

We investigated the possible existence of Hanganutziu-Deicher antigen (HD antigen) on retinoblastoma cells by means of indirect membrane immunofluorescence and a complement-dependent antibody-mediated cytotoxicity test. We prepared antiserum in the chicken by immunization with purified equine hematoside highly specific to HD antigen. Three kinds of retinoblastoma cell lines, Y-79, WERI-Rb 1, and TOTL-1, showed positive membrane staining. Y-79 and TOTL-1 cells were also confirmed by the cytotoxicity test to possess HD antigen. Retinoblastoma cells freshly isolated from two patients had a positive membrane immunofluorescence. These results indicated that HD antigen was expressed in human retinoblastoma cells in vitro as well as in vivo.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6351622     DOI： 10.1016/s0002-9394(14)77822-5

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN： 0002-9394            Impact factor:   5.258


  11 in total

Review 1.  The diagnosis of retinoblastoma.

Authors:  D H Abramson
Journal:  Bull N Y Acad Med       Date:  1988-05

2.  LC-MS analysis of polyclonal human anti-Neu5Gc xeno-autoantibodies immunoglobulin G Subclass and partial sequence using multistep intravenous immunoglobulin affinity purification and multienzymatic digestion.

Authors:  Qiaozhen Lu; Vered Padler-Karavani; Hai Yu; Xi Chen; Shiaw-Lin Wu; Ajit Varki; William S Hancock
Journal:  Anal Chem       Date:  2012-02-28       Impact factor: 6.986

3.  A naturally occurring 46-amino acid deletion of cytidine monophospho-N-acetylneuraminic acid hydroxylase leads to a change in the intracellular distribution of the protein.

Authors:  S Koyama; T Yamaji; H Takematsu; T Kawano; Y Kozutsumi; A Suzuki; T Kawasaki
Journal:  Glycoconj J       Date:  1996-06       Impact factor: 2.916

4.  Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression.

Authors:  Maria Hedlund; Vered Padler-Karavani; Nissi M Varki; Ajit Varki
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-18       Impact factor: 11.205

Review 5.  Involvement of a non-human sialic Acid in human cancer.

Authors:  Annie N Samraj; Heinz Läubli; Nissi Varki; Ajit Varki
Journal:  Front Oncol       Date:  2014-02-19       Impact factor: 6.244

6.  Detection of gangliosides as N-glycolylneuraminic acid-specific tumor-associated Hanganutziu-Deicher antigen in human retinoblastoma cells.

Authors:  H Higashi; T Sasabe; Y Fukui; M Maru; S Kato
Journal:  Jpn J Cancer Res       Date:  1988-08

7.  Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells.

Authors:  Denise Dorvignit; Kayluz F Boligan; Ernesto Relova-Hernández; Marilyn Clavell; Armando López; Mayrel Labrada; Hans-Uwe Simon; Alejandro López-Requena; Circe Mesa; Stephan von Gunten
Journal:  Sci Rep       Date:  2019-07-09       Impact factor: 4.379

8.  Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products.

Authors:  Sandra L Diaz; Vered Padler-Karavani; Darius Ghaderi; Nancy Hurtado-Ziola; Hai Yu; Xi Chen; Els C M Brinkman-Van der Linden; Ajit Varki; Nissi M Varki
Journal:  PLoS One       Date:  2009-01-21       Impact factor: 3.240

9.  Establishment of a human monoclonal antibody to Hanganutziu-Deicher antigen as a tumor-associated carbohydrate antigen.

Authors:  O Usuba; Y Fujii; I Miyoshi; M Naiki; F Sendo
Journal:  Jpn J Cancer Res       Date:  1988-12

Review 10.  From "Serum Sickness" to "Xenosialitis": Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc.

Authors:  Chirag Dhar; Aniruddha Sasmal; Ajit Varki
Journal:  Front Immunol       Date:  2019-04-17       Impact factor: 7.561
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.