| Literature DB >> 63516 |
J A Smith, J G Hurrell, S J Leach.
Abstract
The use of Freund's complete adjuvant for immunizing goats with myoglobin produces mainly antibodies directed against antigenic determinants present in the native protein. Only about 9% of the total antibodies produced are directed toward determinants not expressed in tha native molecule. This shows that neither emulsification nor the subsequent in vivo events leading up to the immune response appreciably perturb the conformation of the protein surface.Entities:
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Year: 1977 PMID： 63516
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422