Literature DB >> 6351353

Reproductive toxicity of the glycol ethers.

B D Hardin.   

Abstract

The glycol ethers are an important and widely used class of solvents. Recent studies have demonstrated that ethylene glycol monomethyl ether (EGME), ethylene glycol dimethyl ether (EGdiME), ethylene glycol monoethyl ether (EGEE), and ethylene glycol monoethyl ether acetate (EGEEA) are teratogenic. Other studies have demonstrated that testicular atrophy or infertility follow treatment of males with EGME, ethylene glycol monomethyl ether acetate (EGMEA), EGEE, EGEEA, diethylene glycol dimethyl ether (diEGdiME), and diethylene glycol monoethyl ether (diEGEE). Experimental data are reviewed and structure-activity relationships are speculated upon.

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Year:  1983        PMID： 6351353     DOI： 10.1016/0300-483x(83)90014-8

Source DB:  PubMed          Journal:  Toxicology        ISSN： 0300-483X            Impact factor:   4.221


  15 in total

1.  Small RNAs in Rat Sperm Are a Predictive and Sensitive Biomarker of Exposure to the Testicular Toxicant Ethylene Glycol Monomethyl Ether.

Authors:  Angela R Stermer; Gerardo Reyes; Susan J Hall; Kim Boekelheide
Journal:  Toxicol Sci       Date:  2019-06-01       Impact factor: 4.849

Review 2.  Reproductive toxicology in occupational settings: an update.

Authors:  R Winker; H W Rüdiger
Journal:  Int Arch Occup Environ Health       Date:  2005-07-12       Impact factor: 3.015

3.  Occupational exposure to solvents and male infertility.

Authors:  N Cherry; F Labrèche; J Collins; T Tulandi
Journal:  Occup Environ Med       Date:  2001-10       Impact factor: 4.402

4.  Effects of diethylene glycol monomethyl ether on pregnancy and postnatal development in rats.

Authors:  T Yamano; T Noda; M Shimizu; S Morita; M Nagahama
Journal:  Arch Environ Contam Toxicol       Date:  1993-02       Impact factor: 2.804

5.  Exposure to ethylene glycol ethers and spermatogenic disorders in man: a case-control study.

Authors:  H Veulemans; O Steeno; R Masschelein; D Groeseneken
Journal:  Br J Ind Med       Date:  1993-01

6.  Rat myometrial smooth muscle cells show high levels of gap junctional communication under a variety of culture conditions.

Authors:  R Loch-Caruso; M S Pahl; D R Juberg
Journal:  In Vitro Cell Dev Biol       Date:  1992-02

Review 7.  Toxicity of ethylene glycol monomethyl ether: impact on testicular gene expression.

Authors:  Gargi Bagchi; David J Waxman
Journal:  Int J Androl       Date:  2007-12-30

Review 8.  Occupational exposure to glycol ethers and human congenital malformations.

Authors:  George Maldonado; Elizabeth Delzell; Rochelle W Tyl; Lowell E Sever
Journal:  Int Arch Occup Environ Health       Date:  2003-06-19       Impact factor: 3.015

9.  Interagency regulatory liaison group workshop on reproductive toxicity risk assessment.

Authors:  C A Kimmel; G L Kimmel; V Frankos
Journal:  Environ Health Perspect       Date:  1986-04       Impact factor: 9.031

10.  Developmental effects after inhalation exposure of gravid rabbits and rats to ethylene glycol monoethyl ether.

Authors:  F D Andrew; B D Hardin
Journal:  Environ Health Perspect       Date:  1984-08       Impact factor: 9.031
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