Literature DB >> 6350475

A randomised controlled study of intravenous acyclovir (Zovirax) against placebo in adults with chickenpox.

W Al-Nakib, S Al-Kandari, D M El-Khalik, A M El-Shirbiny.   

Abstract

In a double-blind, randomised, placebo-controlled trial of intravenous acyclovir (ACV) in normal adults with chickenpox, the drug was shown to have a significant effect on the duration of vesicles, on virus counts after one day's treatment and in lowering the body temperature on the third, fourth and sixth days of treatment. There were no significant effects on the duration of symptoms or on the evolution of the rash. No adverse effects of acyclovir were seen.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6350475     DOI: 10.1016/s0163-4453(83)94129-4

Source DB:  PubMed          Journal:  J Infect        ISSN: 0163-4453            Impact factor:   6.072


  5 in total

1.  Chickenpox in pregnancy. Acyclovir for uncomplicated chickenpox?

Authors:  C H Mann; M P Wyldes
Journal:  BMJ       Date:  1993-05-29

2.  Varicella zoster myocarditis progressing to cardiomyopathy and cardiac transplantation.

Authors:  A Tsintsof; W J Delprado; A M Keogh
Journal:  Br Heart J       Date:  1993-07

Review 3.  Acyclovir. A review of its pharmacodynamic properties and therapeutic efficacy.

Authors:  D M Richards; A A Carmine; R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1983-11       Impact factor: 9.546

Review 4.  Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  J J O'Brien; D M Campoli-Richards
Journal:  Drugs       Date:  1989-03       Impact factor: 9.546

Review 5.  Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatment.

Authors:  R Snoeck; G Andrei; E De Clercq
Journal:  Drugs       Date:  1999-02       Impact factor: 11.431

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.