Literature DB >> 6350085

An immunofluorescence study of anti-pancreatic islet cell antibodies in the spontaneously diabetic BB Wistar rat.

D R Pollard, K Gupta, L Mancino, I Hynie.   

Abstract

Sera from BB Wistar rats and Wistar control rats were evaluated for the presence of islet cell antibodies in a prospective study using an indirect immunofluorescence assay on pancreatic islet cell suspensions from cultured rat islets. Islet cell surface antibodies were detected in sera from all animals of the spontaneously diabetic BB Wistar rat colony. The antibody could be detected well before the clinical onset of the disease and was present throughout the course of study of all diabetic animals. Sera from control Wistar rats were negative when tested for this antibody.

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Year:  1983        PMID： 6350085     DOI： 10.1007/bf00251898

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  16 in total

1.  Autoimmunity and the endocrine pancreas.

Authors:  D Doniach; G F Bottazzo
Journal:  Pathobiol Annu       Date:  1977

2.  Incidence and significance of islet-cell autoantibodies in different types of diabetes mellitus.

Authors:  G F Del Prete; C Betterle; D Padovan; G Erle; A Toffolo; G Bersahi
Journal:  Diabetes       Date:  1977-10       Impact factor: 9.461

Review 3.  The diabetic syndrome of the 'BB' Wistar rat: possible relevance to type 1 (insulin-dependent) diabetes in man.

Authors:  E B Marliss; A F Nakhooda; P Poussier; A A Sima
Journal:  Diabetologia       Date:  1982-04       Impact factor: 10.122

4.  The use of ficoll in the preparation of viable islets of langerhans from the rat pancreas.

Authors:  D W Scharp; C B Kemp; M J Knight; W F Ballinger; P E Lacy
Journal:  Transplantation       Date:  1973-12       Impact factor: 4.939

5.  Purification of monolayer cell cultures of the endocrine pancreas.

Authors:  J T Braaten; U Järlfors; D S Smith; D H Mintz
Journal:  Tissue Cell       Date:  1975       Impact factor: 2.466

6.  The spontaneously diabetic Wistar rat. Metabolic and morphologic studies.

Authors:  A F Nakhooda; A A Like; C I Chappel; F T Murray; E B Marliss
Journal:  Diabetes       Date:  1977-02       Impact factor: 9.461

7.  Islet-cell-surface antibodies in juvenile diabetes mellitus.

Authors:  A Lernmark; Z R Freedman; C Hofmann; A H Rubenstein; D F Steiner; R L Jackson; R J Winter; H S Traisman
Journal:  N Engl J Med       Date:  1978-08-24       Impact factor: 91.245

8.  Cytotoxic autoantibodies to beta cells in the serum of patients with insulin-dependent diabetes mellitus.

Authors:  M J Dobersen; J E Scharff; F Ginsberg-Fellner; A L Notkins
Journal:  N Engl J Med       Date:  1980-12-25       Impact factor: 91.245

9.  Gastric parietal cell and other autoantibodies in the BB rat.

Authors:  M Elder; N Maclaren; W Riley; T McConnell
Journal:  Diabetes       Date:  1982-04       Impact factor: 9.461

10.  Islet cell surface antibodies and lymphocyte antibodies in the spontaneously diabetic BB Wistar rat.

Authors:  T Dyrberg; A F Nakhooda; S Baekkeskov; A Lernmark; P Poussier; E B Marliss
Journal:  Diabetes       Date:  1982-03       Impact factor: 9.461
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  2 in total

Review 1.  Altered immunity and diabetes in the BB rat.

Authors:  J F Yale; E B Marliss
Journal:  Clin Exp Immunol       Date:  1984-07       Impact factor: 4.330

2.  Characterization of monoclonal islet cell reactive autoantibodies from the diabetic biobreeding (BB/OK) rat.

Authors:  B Ziegler; S Witt; K D Kohnert; M Schlosser; P Augstein; D Michaelis; I Klöting; M Ziegler
Journal:  Acta Diabetol       Date:  1993       Impact factor: 4.280
  2 in total

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