| Literature DB >> 6350039 |
M Kukhanova, L Victorova, A Krayevsky.
Abstract
The molecular mechanism of action of the alkaloid lycorine has been revised. According to our results, lycorine inhibits the binding of CACCA-Leu comes from Ac to the donor site of the peptidyltransferase center of wheat-germ ribosomes, whereas the transpeptidation reaction in the system with the minimal model donor is not inhibited. The equilibrium constant of CACCA-Leu comes from Ac to the donor site of 80 S ribosomes is measured.Entities:
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Year: 1983 PMID： 6350039 DOI： 10.1016/0014-5793(83)80951-x
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124