Literature DB >> 6349842

Note on the stability of mefloquine hydrochloride in aqueous solution.

R Reber-Liske.   

Abstract

Using Desjardins' technique for the testing of antimalarials against Plasmodium falciparum in vitro, a 4-year-old solution of mefloquine in water (10(-3) mol/litre) was compared with a freshly prepared solution.The results showed that the two solutions had almost identical activity. There was no evidence for any instability of mefloquine in aqueous solution.

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Year:  1983        PMID: 6349842      PMCID: PMC2536110     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  6 in total

1.  Fansidar resistant falciparum malaria acquired in South East Asia.

Authors:  F Black; I Bygbjerg; P Effersøe; G Gomme; S Jepsen; G A Jensen
Journal:  Trans R Soc Trop Med Hyg       Date:  1981       Impact factor: 2.184

2.  [In vitro assessment of the sensitivity of P. falciparum to mefloquine (author's transl)].

Authors:  P Druilhe; F Janot; H Felix; M Gentilini
Journal:  Nouv Presse Med       Date:  1981-02-07

3.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

4.  Factors affecting diazepam infusion: solubility, administration-set composition, and flow rate.

Authors:  N A Mason; S Cline; M L Hyneck; R R Berardi; N F Ho; G L Flynn
Journal:  Am J Hosp Pharm       Date:  1981-10

5.  Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique.

Authors:  R E Desjardins; C J Canfield; J D Haynes; J D Chulay
Journal:  Antimicrob Agents Chemother       Date:  1979-12       Impact factor: 5.191

6.  Effect of inline filtration on the potency of low-dose drugs.

Authors:  D L Butler; J M Munson; P P DeLuca
Journal:  Am J Hosp Pharm       Date:  1980-07
  6 in total

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