Literature DB >> 6349397

In vitro cultivation of the exoerythrocytic stage of Plasmodium berghei in a hepatoma cell line.

M R Hollingdale, P Leland, A L Schwartz.   

Abstract

When inoculated with sporozoites of Plasmodium berghei, a line of hepatoma cells (HepG2-A16) derived from human liver supports the complete asexual developmental cycle of the exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes. Subinoculation of merozoites into mice induced a red blood cell infection.

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Year:  1983        PMID: 6349397     DOI: 10.4269/ajtmh.1983.32.682

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  24 in total

Review 1.  Live and let die: manipulation of host hepatocytes by exoerythrocytic Plasmodium parasites.

Authors:  Angelika Sturm; Volker Heussler
Journal:  Med Microbiol Immunol       Date:  2007-04-05       Impact factor: 3.402

Review 2.  A pre-emptive strike against malaria's stealthy hepatic forms.

Authors:  Dominique Mazier; Laurent Rénia; Georges Snounou
Journal:  Nat Rev Drug Discov       Date:  2009-11       Impact factor: 84.694

3.  Quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry.

Authors:  Photini Sinnis; Patricia De La Vega; Alida Coppi; Urszula Krzych; Maria M Mota
Journal:  Methods Mol Biol       Date:  2013

Review 4.  Current therapies and future possibilities for drug development against liver-stage malaria.

Authors:  Rene Raphemot; Dora Posfai; Emily R Derbyshire
Journal:  J Clin Invest       Date:  2016-06-01       Impact factor: 14.808

Review 5.  Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections.

Authors:  Alexis Kaushansky; Sebastian A Mikolajczak; Marissa Vignali; Stefan H I Kappe
Journal:  Cell Microbiol       Date:  2014-03-06       Impact factor: 3.715

Review 6.  The biology of tissue forms and other asexual stages in mammalian plasmodia.

Authors:  J P Verhave; J F Meis
Journal:  Experientia       Date:  1984-12-15

Review 7.  New answers through chemotherapy?

Authors:  W Peters
Journal:  Experientia       Date:  1984-12-15

8.  Class II-restricted protective immunity induced by malaria sporozoites.

Authors:  Giane A Oliveira; Kota Arun Kumar; J Mauricio Calvo-Calle; Caroline Othoro; David Altszuler; Victor Nussenzweig; Elizabeth H Nardin
Journal:  Infect Immun       Date:  2007-12-26       Impact factor: 3.441

9.  Novel type II fatty acid biosynthesis (FAS II) inhibitors as multistage antimalarial agents.

Authors:  Florian C Schrader; Serghei Glinca; Julia M Sattler; Hans-Martin Dahse; Gustavo A Afanador; Sean T Prigge; Michael Lanzer; Ann-Kristin Mueller; Gerhard Klebe; Martin Schlitzer
Journal:  ChemMedChem       Date:  2013-01-22       Impact factor: 3.466

Review 10.  Cultivation of plasmodium spp.

Authors:  Frederick L Schuster
Journal:  Clin Microbiol Rev       Date:  2002-07       Impact factor: 26.132

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