Literature DB >> 6348532

A micronucleus method for detection of meiotic micronuclei in male germ cells of mammals.

A D Tates, A J Dietrich, N de Vogel, I Neuteboom, A Bos.   

Abstract

A new rapid micronucleus method is presented for the detection of chromosomal damage induced in spermatocyte stages of mammals. Analysis of micronuclei is done in early spermatids that have been isolated from testis tubules in a special testis isolation medium supplemented with enzymes (collagenase, trypsin and DNAase).

Mesh:

Year:  1983        PMID: 6348532     DOI: 10.1016/0165-7992(83)90111-2

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  2 in total

1.  Detection of mitomycin C-induced testicular toxicity by micronucleus assay in mice.

Authors:  Soichi Nakagawa; Chisato Mori
Journal:  Reprod Med Biol       Date:  2003-04-30

Review 2.  The micronucleus test-most widely used in vivo genotoxicity test.

Authors:  Makoto Hayashi
Journal:  Genes Environ       Date:  2016-10-01
  2 in total

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