Literature DB >> 6348289

Proteus morgani is less frequently associated with urinary tract infections than Proteus mirabilis--an explanation.

B W Senior.   

Abstract

The metabolic activities of faecal and urinary strains of Proteus morgani and P. mirabilis were compared. Regardless of origin, the generation time of P. morgani strains in urine was approximately twice as long as that of the P. mirabilis strains. Urease synthesis was constitutive in P. morgani strains but required induction with urea in the P. mirabilis strains. In the presence of urea, the P. mirabilis strains liberated ammonia more rapidly and produced alkaline conditions more quickly than P. morgani strains, although they synthesized much less urease. These characteristics may place P. morgani strains at a disadvantage in comparison with P. mirabilis strains in their ability to cause urinary tract infections.

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Year:  1983        PMID: 6348289     DOI: 10.1099/00222615-16-3-317

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN: 0022-2615            Impact factor:   2.472


  17 in total

Review 1.  Microbial ureases: significance, regulation, and molecular characterization.

Authors:  H L Mobley; R P Hausinger
Journal:  Microbiol Rev       Date:  1989-03

2.  Regulation of the swarming inhibitor disA in Proteus mirabilis.

Authors:  Bree A Szostek; Philip N Rather
Journal:  J Bacteriol       Date:  2013-05-17       Impact factor: 3.490

3.  Loss of the waaL O-antigen ligase prevents surface activation of the flagellar gene cascade in Proteus mirabilis.

Authors:  Randy M Morgenstein; Katy M Clemmer; Philip N Rather
Journal:  J Bacteriol       Date:  2010-04-09       Impact factor: 3.490

4.  Proteinases of Proteus spp.: purification, properties, and detection in urine of infected patients.

Authors:  L M Loomes; B W Senior; M A Kerr
Journal:  Infect Immun       Date:  1992-06       Impact factor: 3.441

5.  Urinary pathogenicity of Proteus mirabilis strains isolated from faeces or urine.

Authors:  P G Peerbooms; A M Verweij; P L Oe; D M MacLaren
Journal:  Antonie Van Leeuwenhoek       Date:  1986       Impact factor: 2.271

6.  Unique developmental characteristics of the swarm and short cells of Proteus vulgaris and Proteus mirabilis.

Authors:  J O Falkinham; P S Hoffman
Journal:  J Bacteriol       Date:  1984-06       Impact factor: 3.490

7.  Development of an intranasal vaccine to prevent urinary tract infection by Proteus mirabilis.

Authors:  Xin Li; C Virginia Lockatell; David E Johnson; M Chelsea Lane; John W Warren; Harry L T Mobley
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

8.  Morganella morganii urease: purification, characterization, and isolation of gene sequences.

Authors:  L T Hu; E B Nicholson; B D Jones; M J Lynch; H L Mobley
Journal:  J Bacteriol       Date:  1990-06       Impact factor: 3.490

9.  Molecular characterization of a TEM-21 beta-lactamase in a clinical isolate of Morganella morganii.

Authors:  F Tessier; C Arpin; A Allery; C Quentin
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

10.  Proteus mirabilis mutants defective in swarmer cell differentiation and multicellular behavior.

Authors:  R Belas; D Erskine; D Flaherty
Journal:  J Bacteriol       Date:  1991-10       Impact factor: 3.490

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