Literature DB >> 6348032

Alternative explanation for excision repair deficiency caused by the polAex1 mutation.

A F Wahl, J W Hockensmith, S Kowalski, R A Bambara.   

Abstract

An investigation of the mechanism of the polAex1 mutation in vitro suggested that the excision repair deficiency observed in vivo does not result from an inability of the enzyme to nick translate. The defect appears to reside in the inability of the enzyme to effectively generate a nick structure to serve as a substrate for DNA ligase.

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Year:  1983        PMID： 6348032      PMCID： PMC217772          DOI： 10.1128/jb.155.2.922-925.1983

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  9 in total

1.  Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. II. The polAex1 mutation.

Authors:  D Uyemura; D C Eichler; I R Lehman
Journal:  J Biol Chem       Date:  1976-07-10       Impact factor: 5.157

Review 2.  DNA repair in bacteria and mammalian cells.

Authors:  P C Hanawalt; P K Cooper; A K Ganesan; C A Smith
Journal:  Annu Rev Biochem       Date:  1979       Impact factor: 23.643

3.  Strand displacement during deoxyribonucleic acid synthesis at single strand breaks.

Authors:  Y Masamune; C C Richardson
Journal:  J Biol Chem       Date:  1971-04-25       Impact factor: 5.157

4.  Kinetic characteristics which distinguish two forms of calf thymus DNA polymerase alpha.

Authors:  J W Hockensmith; R A Bambara
Journal:  Biochemistry       Date:  1981-01-06       Impact factor: 3.162

5.  Transient generation of displaced single-stranded DNA during nick translation.

Authors:  R C Lundquist; B M Olivera
Journal:  Cell       Date:  1982-11       Impact factor: 41.582

6.  A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region.

Authors:  A Sancar; W D Rupp
Journal:  Cell       Date:  1983-05       Impact factor: 41.582

7.  Short deoxyribonucleic acid repair patch length in Escherichia coli is determined by the processive mechanism of deoxyribonucleic acid polymerase I.

Authors:  S W Matson; R A Bambara
Journal:  J Bacteriol       Date:  1981-04       Impact factor: 3.490

8.  Reversible binding of Pi by beef heart mitochondrial adenosine triphosphatase.

Authors:  H S Penefsky
Journal:  J Biol Chem       Date:  1977-05-10       Impact factor: 5.157

9.  A conditional lethal mutant of Escherichia coli K12 defective in the 5' leads to 3' exonuclease associated with DNA polymerase I.

Authors:  E B Konrad; I R Lehman
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205
  9 in total
  3 in total

1.  DNA polymerase I in constitutive stable DNA replication in Escherichia coli.

Authors:  T Kogoma; R R Maldonado
Journal:  J Bacteriol       Date:  1997-04       Impact factor: 3.490

2.  Requirement for the polymerization and 5'-->3' exonuclease activities of DNA polymerase I in initiation of DNA replication at oriK sites in the absence of RecA in Escherichia coli rnhA mutants.

Authors:  Y Cao; T Kogoma
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490

3.  Method for determining whether a gene of Escherichia coli is essential: application to the polA gene.

Authors:  C M Joyce; N D Grindley
Journal:  J Bacteriol       Date:  1984-05       Impact factor: 3.490
  3 in total

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