Literature DB >> 6347898

Clostridium tetani growth and toxin production in the intestines of germfree rats.

C L Wells, E Balish.   

Abstract

Germfree rats were challenged orally and intrarectally with spores of Clostridium tetani. Although C. tetani spores remained viable in the intestinal tract, they were unable to germinate. Germfree rats were then challenged orally with vegetative cells of C. tetani. Vegetative cells were able to colonize the intestinal tract, replicate, and produce toxin. Tetanus antitoxin, but no tetanus toxin, was detected in the sera of monoassociated rats.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6347898      PMCID： PMC264714          DOI： 10.1128/iai.41.2.826-828.1983

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  8 in total

1.  Use of anaerobic glove boxes for the cultivation of strictly anaerobic bacteria.

Authors:  A Aranki; R Freter
Journal:  Am J Clin Nutr       Date:  1972-12       Impact factor: 7.045

2.  Susceptibility to enteric botulinum colonization of antibiotic-treated adult mice.

Authors:  D H Burr; H Sugiyama
Journal:  Infect Immun       Date:  1982-04       Impact factor: 3.441

3.  Quantitative evidence of intestinal colonization by Clostridium botulinum in four cases of infant botulism.

Authors:  B W Wilcke; T F Midura; S S Arnon
Journal:  J Infect Dis       Date:  1980-04       Impact factor: 5.226

4.  Intraintestinal toxin in infant mice challenged intragastrically with Clostridium botulinum spores.

Authors:  H Sugiyama; D C Mills
Journal:  Infect Immun       Date:  1978-07       Impact factor: 3.441

5.  Microbial ecological basis of infant botulism as studied with germfree mice.

Authors:  L J Moberg; H Sugiyama
Journal:  Infect Immun       Date:  1979-08       Impact factor: 3.441

6.  The rat as an animal model for infant botulism.

Authors:  L J Moberg; H Sugiyama
Journal:  Infect Immun       Date:  1980-08       Impact factor: 3.441

7.  Intestinal infection and toxin production by Clostridium botulinum as one cause of sudden infant death syndrome.

Authors:  S S Arnon; T F Midura; K Damus; R M Wood; J Chin
Journal:  Lancet       Date:  1978-06-17       Impact factor: 79.321

8.  Resistance of mice with limited intestinal flora to enteric colonization by Clostridium botulinum.

Authors:  C L Wells; H Sugiyama; S E Bland
Journal:  J Infect Dis       Date:  1982-12       Impact factor: 5.226
  8 in total
  2 in total

1.  Risk-based immunization policies and tuberculosis screening practices for animal care and research workers in the United States: survey results and recommendations.

Authors:  Benjamin J Weigler; Donna R Cooper; F Claire Hankenson
Journal:  J Am Assoc Lab Anim Sci       Date:  2012       Impact factor: 1.232

Review 2.  Vaccine Production to Protect Animals Against Pathogenic Clostridia.

Authors:  Nicolas E Zaragoza; Camila A Orellana; Glenn A Moonen; George Moutafis; Esteban Marcellin
Journal:  Toxins (Basel)       Date:  2019-09-11       Impact factor: 4.546
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.