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Literature DB >> 6347800

Distribution of secretory component in non-cancerous human gastric mucosa.

S Maeda, Y Akahonai, M Mori, K Yonezawa, T Endo, M Arashi, A Yachi.

Abstract

Immunological detection of secretory component (SC) in non-cancerous human gastric mucosa was carried out by the peroxidase-anti-peroxidase (PAP) method using several fixatives. SC was detected in the generative zone or mucous neck of normal gastric mucosa without intestinal metaplasia (IM) and in absorptive cells of IM of the stomach. The deep part of complete type IM showed a larger amount of SC than the superficial part. These findings suggested that the appearance of SC in gastric mucosa would be relevant to the immunity of glandular epithelium. In addition, SC was also detected in pyloric gland cells in specimens fixed with cold 95% ethanol. From these results, SC was considered to be a normal constituent and one of the developmental proteins in the gastric mucosa.

Entities: Chemical Disease

Mesh：

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Year: 1983 PMID： 6347800 DOI： 10.1007/bf02774964

Source DB: PubMed Journal: Gastroenterol Jpn ISSN： 0435-1339

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References

21 in total

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Distribution of secretory component in non-cancerous human gastric mucosa.

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Review 4. Secretory immunoglobulins.

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