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Literature DB >> 6347472

Impaired primary antibody response in experimental nephrotic syndrome.

Abstract

The primary antibody response to sheep red blood cells (SRBC) is reduced in rats with aminonucleoside of puromycin (AP) nephrosis, as measured by haemagglutination and IgM antibody forming spleen cells (AFC). Since rats immunized 1 day after AP administration had a normal antibody response, these studies suggest that the impaired immune response in nephrotic rats is not due to a direct effect of AP but that it is secondary to the nephrotic state.

Entities: Chemical Disease Species

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Year: 1983 PMID： 6347472 PMCID： PMC1536047

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

14 in total

1. The role of prostaglandins in the control of the primary 19S immune response to sRBC.

Authors: D R Webb; I Nowowiejski
Journal: Cell Immunol Date: 1977-09 Impact factor: 4.868

2. Determination of total and merecaptothanol-resistant antibody in the same serum sample.

Authors: D W Scott; R K Gershon
Journal: Clin Exp Immunol Date: 1970-02 Impact factor: 4.330

3. Unilateral renal disease in the rat. I. Clinical, morphologic, and glomerular mesangial functional features of the experimental model produced by renal perfusion with aminonucleoside.

Authors: J R Hoyer; S M Mauer; A F Michael
Journal: J Lab Clin Med Date: 1975-05

Review 4. Regulation of the immune response by prostaglandins.

Authors: J S Goodwin; D R Webb
Journal: Clin Immunol Immunopathol Date: 1980-01

5. Recurrent pneumococcal sepsis and defective opsonization after pneumococcal capsular polysaccharide vaccine in a child with nephrotic syndrome.

Authors: D H Moore; P G Shackelford; A M Robson; G M Rose
Journal: J Pediatr Date: 1980-05 Impact factor: 4.406

6. Metabolism of puromycin aminonucleoside in the normal, "pre-nephrotic," and nephrotic rat.

Authors: R F Derr; C S Alexander; H T Nagasawa
Journal: Proc Soc Exp Biol Med Date: 1967-05

7. Heligmosomoides polygyrus (=Nematospiroides dubius): suppression of antibody response to orally administered sheep erythrocytes in infected mice.

Authors: R G Shimp; R B Crandall; C A Crandall
Journal: Exp Parasitol Date: 1975-10 Impact factor: 2.011

Impaired primary antibody response in experimental nephrotic syndrome.

1. The role of prostaglandins in the control of the primary 19S immune response to sRBC.

2. Determination of total and merecaptothanol-resistant antibody in the same serum sample.

3. Unilateral renal disease in the rat. I. Clinical, morphologic, and glomerular mesangial functional features of the experimental model produced by renal perfusion with aminonucleoside.

Review 4. Regulation of the immune response by prostaglandins.

5. Recurrent pneumococcal sepsis and defective opsonization after pneumococcal capsular polysaccharide vaccine in a child with nephrotic syndrome.

6. Metabolism of puromycin aminonucleoside in the normal, "pre-nephrotic," and nephrotic rat.

7. Heligmosomoides polygyrus (=Nematospiroides dubius): suppression of antibody response to orally administered sheep erythrocytes in infected mice.

8. Failure of pneumococcal vaccine to prevent Streptococcus pneumoniae sepsis in nephrotic children.

9. Lymphocyte blastogenesis in nephrotic syndrome.

10. Transfer of aminonucleoside nephrosis by renal transplantation.

1. Hypogammaglobulinaemia in nephrotic rats is attributable to hypercatabolism of IgG.

Review 2. Membranous nephropathy in the older adult: epidemiology, diagnosis and management.