| Literature DB >> 6345764 |
R E Zimmerman, R S Nevin, D J Allen, C D Jones, M E Goettel, P J Burck.
Abstract
Acrosin and acrosomal hyaluronidase were inhibited by tetradecyl sodium sulphate (TDSS) in vitro at concentrations of less than 10(-4) M. TDSS prevented the removal in vitro of the cumulus oophorus by testicular hyaluronidase and the zona pellucida by acrosin. TDSS had a contraceptive effect in rabbits when administered intravaginally before coitus or released at levels of 1-3 micrograms/day from intrauterine silicone rubber devices.Entities:
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Year: 1983 PMID： 6345764 DOI： 10.1530/jrf.0.0680257
Source DB: PubMed Journal: J Reprod Fertil ISSN： 0022-4251