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Literature DB >> 6345715

Cell membrane perturbation of resting T cells and thymocytes causes display of activation antigens.

R S Mittler, P E Rao, M A Talle, R Look, G Goldstein.

Abstract

Three human lymphocyte antigens recognized by monoclonal antibodies OKIa1, OKT9, and OKT10 were found to be minimally represented on resting peripheral T cells (all three) and thymocytes (OKIa1 and OKT9). These antigens, which are present on "activated" T cells, were promptly displayed on "resting" T cells or thymocytes following cross-linking of surface-bound monoclonal antibody by horse alpha-mouse IgG. These experiments suggested that membrane perturbations may induce the expression of certain antigens that are normally present in an unexpressed form in resting cells.

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Year: 1983 PMID： 6345715 PMCID： PMC2187085 DOI： 10.1084/jem.158.1.99

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

23 in total

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Journal: J Exp Med Date: 1978-06-01 Impact factor: 14.307

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Authors: E L Reinherz; P C Kung; G Goldstein; S F Schlossman
Journal: Proc Natl Acad Sci U S A Date: 1979-08 Impact factor: 11.205

6. A radio-ligand receptor assay for the long-acting thyroid stimulator. Inhibition by the long-acting thyroid stimulator of the binding of radioiodinated thyroid-stimulating hormone to human thyroid membranes.

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Journal: J Exp Med Date: 1979-12-01 Impact factor: 14.307

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Journal: J Exp Med Date: 1975-06-01 Impact factor: 14.307

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Authors: R L Evans; T J Faldetta; R E Humphreys; D M Pratt; E J Yunis; S F Schlossman
Journal: J Exp Med Date: 1978-11-01 Impact factor: 14.307

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Journal: J Exp Med Date: 1980-01-01 Impact factor: 14.307

8 in total

1. Major histocompatibility complex class II invariant chain expression in non-antigen-presenting cells.

Authors: H Veenstra; W F Ferris; P J Bouic
Journal: Immunology Date: 2001-06 Impact factor: 7.397

2. Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens.

Authors: F Pallone; S Fais; O Squarcia; L Biancone; P Pozzilli; M Boirivant
Journal: Gut Date: 1987-06 Impact factor: 23.059

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Authors: B L Davidson; J Faust; S Pessano; R P Daniele; G Rovera
Journal: J Clin Invest Date: 1985-07 Impact factor: 14.808

4. HLA-DR antigens on colonic epithelial cells in inflammatory bowel disease: I. Relation to the state of activation of lamina propria lymphocytes and to the epithelial expression of other surface markers.

Authors: S Fais; F Pallone; O Squarcia; L Biancone; F Ricci; P Paoluzi; M Boirivant
Journal: Clin Exp Immunol Date: 1987-06 Impact factor: 4.330