Literature DB >> 6345673

The J744.2 cell line presents antigen in an I region restricted manner.

S Schwarzbaum, B Diamond.   

Abstract

We report here the ability of a murine macrophage-like cell line, J774.2, to present antigen to primed T cells in a genetically restricted manner. J774.2 is a subclone derived from the reticulum cell sarcoma cell line, J774. Like mature macrophages, J774.2 possesses Fc receptors for all immunoglobulin G (IgG) subclasses; it is capable of performing Fc-mediated phagocytosis, and it secretes both lysozyme and plasminogen activator.

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Year:  1983        PMID： 6345673

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  3 in total

1.  Generation and analysis of clonal IgM- and IgG-producing human B cell lines expressing an anti-DNA-associated idiotype.

Authors:  A J Manheimer-Lory; A Davidson; D Watkins; N R Hannigan; B A Diamond
Journal:  J Clin Invest       Date:  1991-05       Impact factor: 14.808

2.  In vitro cellular immune response to measles viral glycoproteins: role of the antigen vector.

Authors:  O Bakouche; B Mougin; D Gerlier
Journal:  Immunology       Date:  1987-12       Impact factor: 7.397

3.  Intracellular activity of zidovudine (3'-azido-3'-deoxythymidine, AZT) against Salmonella typhimurium in the macrophage cell line J774-2.

Authors:  J L Herrmann; P H Lagrange
Journal:  Antimicrob Agents Chemother       Date:  1992-05       Impact factor: 5.191
  3 in total

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