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Literature DB >> 6345510

Inhibition of RNA synthesis by oxolinic acid is unrelated to average DNA supercoiling.

Abstract

Oxolinic acid reduced RNA synthesis rates whether chromosome supercoiling decreased, increased, or remained unchanged. Thus, inhibition of RNA synthesis by oxolinic acid appears to involve factors other than average DNA supercoiling level. Coumermycin A1 caused RNA synthesis rates to increase or decrease roughly in parallel with DNA supercoiling.

Entities: Chemical

Mesh：

Substances：

Year: 1983 PMID： 6345510 PMCID： PMC217697 DOI： 10.1128/jb.155.1.420-423.1983

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

22 in total

1. Effects of supercoiling on transcription from bacteriophage PM2 deoxyribonucleic acid.

Authors: J P Richardson
Journal: Biochemistry Date: 1974-07-16 Impact factor: 3.162

2. Inhibition of ribonucleic acid synthesis by nalidixic acid in Escherichia coli.

Authors: G T Javor
Journal: J Bacteriol Date: 1974-10 Impact factor: 3.490

3. Effect of circularity and superhelicity on transcription from bacteriophagelambda DNA.

Authors: P Botchan; J C Wang; H Echols
Journal: Proc Natl Acad Sci U S A Date: 1973-11 Impact factor: 11.205

4. The interaction of closed circular DNA with intercalative dyes. I. The superhelix density of SV40 DNA in the presence and absence of dye.

Authors: W Bauer; J Vinograd
Journal: J Mol Biol Date: 1968-04-14 Impact factor: 5.469

5. Supercoiling of polyoma virus DNA measured by its interaction with ethidium bromide.

Authors: L V Crawford; M J Waring
Journal: J Mol Biol Date: 1967-04-14 Impact factor: 5.469

6. Attachment of nascent RNA molecules to superhelical DNA.

Authors: J P Richardson
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

7. An electron microscopic comparison of transcription on linear and superhelical DNA.

Authors: P Botchan
Journal: J Mol Biol Date: 1976-07-25 Impact factor: 5.469

8. Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

Authors: M Gellert; M H O'Dea; T Itoh; J Tomizawa
Journal: Proc Natl Acad Sci U S A Date: 1976-12 Impact factor: 11.205

9. Template activities of the phi X-174 replicative allomorphic deoxyribonucleic acids.

Authors: Y Hayashi; M Hayashi
Journal: Biochemistry Date: 1971-11 Impact factor: 3.162

10. Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity.

Authors: M Gellert; K Mizuuchi; M H O'Dea; T Itoh; J I Tomizawa
Journal: Proc Natl Acad Sci U S A Date: 1977-11 Impact factor: 11.205

23 in total

1. A mer-lux transcriptional fusion for real-time examination of in vivo gene expression kinetics and promoter response to altered superhelicity.

Authors: C W Condee; A O Summers
Journal: J Bacteriol Date: 1992-12 Impact factor: 3.490

2. Lethal action of quinolones against a temperature-sensitive dnaB replication mutant of Escherichia coli.

Authors: Xilin Zhao; Muhammad Malik; Nymph Chan; Alex Drlica-Wagner; Jian-Ying Wang; Xinying Li; Karl Drlica
Journal: Antimicrob Agents Chemother Date: 2006-01 Impact factor: 5.191

Review 3. DNA gyrase, topoisomerase IV, and the 4-quinolones.

Authors: K Drlica; X Zhao
Journal: Microbiol Mol Biol Rev Date: 1997-09 Impact factor: 11.056

4. Hydrogenase synthesis in Bradyrhizobium japonicum Hupc mutants is altered in sensitivity to DNA gyrase inhibitors.

Authors: P D Novak; R J Maier
Journal: Appl Environ Microbiol Date: 1989-05 Impact factor: 4.792

Review 5. Histonelike proteins of bacteria.

Authors: K Drlica; J Rouviere-Yaniv
Journal: Microbiol Rev Date: 1987-09