Literature DB >> 6345038

Graves' disease: in situ localization of lymphoid T cell subpopulations.

M C Bene, V Derennes, G Faure, J L Thomas, J Duheille, J Leclere.   

Abstract

An in situ analysis of immunological features in thyroids from 15 Graves' disease patients has been performed. This study included a search for immune complexes visualized near the follicle's basement membranes with fluorescent rabbit antisera to human IgG, IgA, IgM, C1q, C3 and C9. Cellular immunity was investigated on the humoral side by visualization of B cells and plasma cells. Two series of monoclonal antibodies (OKT3, 4 and 8, Leu 1, 2a and 3a) were used to label the infiltrating cells' membrane. These studies demonstrated the prevalence of T cells, a majority of them with OKT8/Leu 2a suppressor/cytotoxic phenotype. No correlation was found between this observation and peripheral blood T cell subsets analysis.

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Year:  1983        PMID： 6345038      PMCID： PMC1535832     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  16 in total

1.  Distribution of T-, B-, and thyroglobulin-binding lymphocytes infiltrating the gland in Graves' disease, Hashimoto's thyroiditis, and de Quervain's thyroiditis.

Authors:  T H Tötterman
Journal:  Clin Immunol Immunopathol       Date:  1978-07

2.  B- and T-lymphocytes in toxic diffuse goitre.

Authors:  L Sköldstam; B Anderberg; K Norrby
Journal:  Clin Exp Immunol       Date:  1978-03       Impact factor: 4.330

3.  Cell-mediated autoimmunity in thyroid disease as studied by the leukocyte migration test; correlation to clinical state and effect of treatment.

Authors:  T H Tötterman; T Mäkinen; A Gordin
Journal:  Acta Endocrinol (Copenh)       Date:  1977-09

4.  Study of circulating immune complexes in thyroid diseases: comparison of Raji cell radioimmunoassay and specific thyroglobulin-antithyroglobulin radioassay.

Authors:  S Mariotti; L J DeGroot; D Scarborough; M E Medof
Journal:  J Clin Endocrinol Metab       Date:  1979-11       Impact factor: 5.958

5.  Studies on suppressor cell function in thyroid diseases.

Authors:  N Aoki; K M Pinnamaneni; L J DeGroot
Journal:  J Clin Endocrinol Metab       Date:  1979-05       Impact factor: 5.958

6.  Human T lymphocytes of inducer and suppressor type occupy different microenvironments.

Authors:  G Janossy; N Tidman; W S Selby; J A Thomas; S Granger; P C Kung; G Goldstein
Journal:  Nature       Date:  1980-11-06       Impact factor: 49.962

7.  Circulating thyroglobulin-antithyroglobulin immune complex in thyroid diseases using enzyme-linked immunoassays.

Authors:  S Ohtaki; Y Endo; K Horinouchi; S Yoshitake; E Ishikawa
Journal:  J Clin Endocrinol Metab       Date:  1981-02       Impact factor: 5.958

8.  Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage.

Authors:  E L Reinherz; P C Kung; G Goldstein; R H Levey; S F Schlossman
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

9.  Evidence for thyroid antigen-reactive T lymphocytes infiltrating the thyroid gland in Graves' disease.

Authors:  T H Tötterman; L C Andersson; P Häyry
Journal:  Clin Endocrinol (Oxf)       Date:  1979-07       Impact factor: 3.478

10.  Suppressor T-lymphocyte deficiency in Graves' disease and Hashimoto's thyroiditis.

Authors:  N Okita; V V Row; R Volpe
Journal:  J Clin Endocrinol Metab       Date:  1981-03       Impact factor: 5.958
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  11 in total

1.  Association between the TAP1 gene codon 637 polymorphism and Graves' disease.

Authors:  Rong-Hsing Chen; Wen-Chi Chen; Ching-Chu Chen; Chang-Hai Tsai; Fuu-Jen Tsai
Journal:  Endocrine       Date:  2004-11       Impact factor: 3.633

2.  Association between the TAP2 gene codon 665 polymorphism and Graves' disease.

Authors:  Rong-Hsing Chen; Tze-Yuan Wang; Wen-Chi Chen; Chang-Hai Tsai; Fuu-Jen Tsai
Journal:  J Clin Lab Anal       Date:  2006       Impact factor: 2.352

3.  Subpopulations of thyroid autoantibody secreting lymphocytes in Graves' and Hashimoto thyroid glands.

Authors:  S M McLachlan; C A Pegg; M C Atherton; S L Middleton; A Dickinson; F Clark; S J Proctor; G Proud; B Rees Smith
Journal:  Clin Exp Immunol       Date:  1986-08       Impact factor: 4.330

4.  Immunological events leading to destructive thyroiditis in the AUG rat.

Authors:  R Hassman; N Solic; B Jasani; R Hall; A M McGregor
Journal:  Clin Exp Immunol       Date:  1988-09       Impact factor: 4.330

5.  Thyroid stimulating immunoglobulin (TSI) synthesis by pokeweed mitogen (PWM) stimulated peripheral blood lymphocytes (PBL) from Graves' disease (GD) patients.

Authors:  B Pautard; J J Rémy; J Charreire
Journal:  Clin Exp Immunol       Date:  1986-11       Impact factor: 4.330

6.  Mechanism and significance of abnormal blood level of beta 2-microglobulin in patients with Graves' disease.

Authors:  X L Han; W X Yie
Journal:  J Tongji Med Univ       Date:  1988

7.  Intrathyroidal HLA-DR expression and T lymphocyte phenotypes in Graves' thyrotoxicosis, Hashimoto's thyroiditis and nodular colloid goitre.

Authors:  R Jansson; A Karlsson; U Forsum
Journal:  Clin Exp Immunol       Date:  1984-11       Impact factor: 4.330

8.  Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease.

Authors:  Z Wu; E R Podack; J M McKenzie; K J Olsen; M Zakarija
Journal:  Clin Exp Immunol       Date:  1994-12       Impact factor: 4.330

9.  Transplantation of human hyperthyroid tissue to the nude mouse. An experimental model.

Authors:  J M Vignaud; A Duprez; M C Bene; J Leclere; G Faure; N Danchin; C Burlet
Journal:  Am J Pathol       Date:  1984-12       Impact factor: 4.307

10.  Cells infiltrating the thyroid in juvenile autoimmune thyroiditis.

Authors:  S Kontiainen; I Lautenschlager; M Nyberg; J Mäenpää
Journal:  Clin Exp Immunol       Date:  1987-01       Impact factor: 4.330
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