| Literature DB >> 6344314 |
L A Miles, J S Greengard, J H Griffin.
Abstract
In order to compare the relative potencies of plasma kallikrein, beta-Factor XIIa, Factor XIa and urokinase as plasminogen activators, plasminogen activation by these proteins was studied using a radiolabeled fibrin plate assay. Urokinase was approximately 20,000 times more active than kallikrein or Factor XIa and 300,000 times more active than beta-Factor XIIa. Kallikrein and Factor XIa were approximately equal in plasminogen activator activity and were 20 times more potent than beta-Factor XIIa.Entities:
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Year: 1983 PMID： 6344314 DOI： 10.1016/0049-3848(83)90244-x
Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944