Literature DB >> 6344220

Nucleotide sequence of the Rasheed rat sarcoma virus oncogene: new mutations.

S Rasheed, G L Norman, G Heidecker.   

Abstract

The nucleotide sequence of the oncogene of the Rasheed strain of rat sarcoma virus was determined. The oncogene (Ra-v-ras) encodes a 29,000-dalton (p29) transforming protein. This protein is distinct from the immunologically related 21,000-dalton protein (p21) of the Harvey murine sarcoma virus in its amino terminus and in having additional mutations in its carboxyl terminus. Although the functional significance of these changes is unknown, they appear to occur only in rat sarcoma virus.

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Year:  1983        PMID： 6344220     DOI： 10.1126/science.6344220

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  NICER elements: a family of nerve growth factor-inducible cAMP-extinguishable retrovirus-like elements.

Authors:  K O Cho; B Minsk; J A Wagner
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

2.  A splicing enhancer in the 3'-terminal c-H-ras exon influences mRNA abundance and transforming activity.

Authors:  D Y Hwang; J B Cohen
Journal:  J Virol       Date:  1997-09       Impact factor: 5.103

3.  GTP-binding domain: three consensus sequence elements with distinct spacing.

Authors:  T E Dever; M J Glynias; W C Merrick
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

4.  Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene.

Authors:  E P Reddy; D Lipman; P R Andersen; S R Tronick; S A Aaronson
Journal:  J Virol       Date:  1985-03       Impact factor: 5.103

5.  Chimeric proteins define variable and essential regions of Ha-ras-encoded protein.

Authors:  D G Lowe; M Ricketts; A D Levinson; D V Goeddel
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

6.  Complete nucleotide sequence of a mouse VL30 retro-element.

Authors:  S E Adams; P D Rathjen; C A Stanway; S M Fulton; M H Malim; W Wilson; J Ogden; L King; S M Kingsman; A J Kingsman
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

7.  Development of transforming function during transduction of proto-ras into Harvey sarcoma virus.

Authors:  M Lang; I Treinies; P H Duesberg; R Kurth; K Cichutek
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

8.  Photoaffinity labeling with GTP of viral p21 ras protein expressed in Escherichia coli.

Authors:  R B Stein; P S Robinson; E M Scolnick
Journal:  J Virol       Date:  1984-05       Impact factor: 5.103

9.  Structure of a Moloney murine leukemia virus-virus-like 30 recombinant: implications for transduction of the c-Ha-ras proto-oncogene.

Authors:  A Makris; C Patriotis; S E Bear; P N Tsichlis
Journal:  J Virol       Date:  1993-03       Impact factor: 5.103

10.  Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).

Authors:  K Cichutek; P H Duesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205
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