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Literature DB >> 6343621

The role of macrophages in immunology.

Abstract

Macrophages play a significant part in immunity and immune responses. They assume a defensive role exhibited by their ability to carry on phagocytosis of parasites and microbes. They regulate lymphocyte activation and proliferation and they are essential in the activation process of T- and B-lymphocytes by antigens and allogenic cells. Enhanced bactericidal activity of "activated macrophages" is based on immunologically linked mechanisms involving lymphocytes. Macrophages kill ingested microbes but the mechanism by which this is accomplished is not completely understood. This paper discusses the role of macrophages in relation to immunity.

Mesh：

Year: 1983 PMID： 6343621 PMCID： PMC2561478

Source DB: PubMed Journal: J Natl Med Assoc ISSN： 0027-9684 Impact factor: 1.798

25 in total

1. Increased chemotactic responses of macrophages from BCG-infected mice.

Authors: M S Meltzer; E E Jones; D A Boetcher
Journal: Cell Immunol Date: 1975-05 Impact factor: 4.868

2. Activated macrophages as cytotoxic effector cells.

Authors: J B Hibbs
Journal: Transplantation Date: 1975-01 Impact factor: 4.939

Review 3. Cellular immunity.

Authors: G B Mackaness; R V Blanden
Journal: Prog Allergy Date: 1967

4. Studies on chemotaxis. VI. Specific chemotaxis in rabbit polymorphonuclear leucocytes and mononuclear cells.

Authors: H U Keller; E Sorkin
Journal: Int Arch Allergy Appl Immunol Date: 1967

5. Studies on cytophilic antibodies. II. The production by guinea-pigs of macrophage cytophilic antibodies to sheep erythrocytes and human serum albumin: relationship to the production of other antibodies and the development of delayed-type hypersensitivity.

Authors: D S Nelson; P Mildenhall
Journal: Aust J Exp Biol Med Sci Date: 1968-02

6. Inhibitor of macrophage migration produced by polymorphonuclear leucocytes.

Authors: P Stastny; M Ziff
Journal: J Reticuloendothel Soc Date: 1970-01

7. Changes in the fine structure of macrophages in experimentally produced tuberculous granulomas in hamsters.

Authors: A Dumont; H Sheldon
Journal: Lab Invest Date: 1965-11 Impact factor: 5.662

8. Activation and mechanism of action of suppressor macrophages.

Authors: A Lichtenstein; R Murahata; M Terpenning; J Cantrell; J Zighelboim
Journal: Cell Immunol Date: 1981-10 Impact factor: 4.868

9. The effect of polymorphonuclear leucocytes on the blastoid transformation of lymphocytes in mixed leucocyte cultures.

Authors: A L Jones
Journal: Transplantation Date: 1966-05 Impact factor: 4.939

10. Secretion of plasminogen activator by stimulated macrophages.

Authors: J C Unkeless; S Gordon; E Reich
Journal: J Exp Med Date: 1974-04-01 Impact factor: 14.307

22 in total

1. Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment.

Authors: Vasundhara Kain; Ganesh V Halade
Journal: J Cell Physiol Date: 2018-09-07 Impact factor: 6.384

2. Docosahexaenoic Acid Alleviates Atopic Dermatitis by Generating Tregs and IL-10/TGF-β-Modified Macrophages via a TGF-β-Dependent Mechanism.

Authors: Sang-Chul Han; Dong-Hwan Koo; Na-Jin Kang; Weon-Jong Yoon; Gyeoung-Jin Kang; Hee-Kyoung Kang; Eun-Sook Yoo
Journal: J Invest Dermatol Date: 2014-11-18 Impact factor: 8.551

Review 3. Current Status on Immunological Therapies for Type 1 Diabetes Mellitus.

Authors: Griselda Lim Loo Xin; Yap Pui Khee; Tan Yoke Ying; Jestin Chellian; Gaurav Gupta; Anil Philip Kunnath; Srinivas Nammi; Trudi Collet; Philip Michael Hansbro; Kamal Dua; Dinesh Kumar Chellappan
Journal: Curr Diab Rep Date: 2019-03-23 Impact factor: 4.810

4. VIP modulates human macrophages phenotype via FPRL1 via activation of RhoA-GTPase and PLC pathways.

Authors: Zeina Harhous; Wissam H Faour; Nabil El Zein
Journal: Inflamm Res Date: 2021-01-27 Impact factor: 4.575

5. Label-free imaging of M1 and M2 macrophage phenotypes in the human dermis in vivo using two-photon excited FLIM.

Authors: Marius Kröger; Jörg Scheffel; Evgeny A Shirshin; Johannes Schleusener; Martina C Meinke; Jürgen Lademann; Marcus Maurer; Maxim E Darvin
Journal: Elife Date: 2022-10-06 Impact factor: 8.713

6. Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells.

Authors: Rapeepat Sangsuwan; Bhasirie Thuamsang; Noah Pacifici; Riley Allen; Hyunsoo Han; Svetlana Miakicheva; Jamal S Lewis
Journal: Cell Mol Bioeng Date: 2020-09-21 Impact factor: 2.321

7. In-vitro indicators of natural resistance and milk-producing ability in dairy buffaloes (Bubalus bubalis).

Authors: Maria Miarelli; Federica Signorelli
Journal: J Appl Anim Welf Sci Date: 2014-08-11 Impact factor: 1.440

8. Dual inhibition of CSF1R and MAPK pathways using supramolecular nanoparticles enhances macrophage immunotherapy.

Authors: Anujan Ramesh; Anthony Brouillard; Sahana Kumar; Dipika Nandi; Ashish Kulkarni
Journal: Biomaterials Date: 2019-10-19 Impact factor: 12.479

9. Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes.

Authors: Christina L Graves; Angela Chen; Victoria Kwon; Celia E Shiau
Journal: iScience Date: 2021-05-03

10. Lycii radicis cortex inhibits glucocorticoid‑induced bone loss by downregulating Runx2 and BMP‑2 expression.

Authors: Bina Lee; Sooyeon Hong; Minsun Kim; Eun-Young Kim; Hi-Joon Park; Hyuk-Sang Jung; Jae-Hyun Kim; Youngjoo Sohn
Journal: Int J Mol Med Date: 2021-06-24 Impact factor: 4.101