Literature DB >> 6343327

Demethoxyrapamycin (AY-24,668), a new antifungal antibiotic.

S N Sehgal, H Baker, C P Eng, K Singh, C Vézina.   

Abstract

Demethoxyrapamycin is a new antifungal antibiotic which is co-produced with rapamycin by Streptomyces hygroscopicus. It was isolated as a minor component during recovery of rapamycin. Its antifungal and antitumor activity is compared with that of rapamycin.

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Year:  1983        PMID： 6343327     DOI： 10.7164/antibiotics.36.351

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

1.  Production of novel rapamycin analogs by precursor-directed biosynthesis.

Authors:  Frank V Ritacco; Edmund I Graziani; Mia Y Summers; T Mark Zabriskie; Ker Yu; Valerie S Bernan; Guy T Carter; Michael Greenstein
Journal:  Appl Environ Microbiol       Date:  2005-04       Impact factor: 4.792

2.  Description of Streptomyces neopeptinius sp. nov., an actinobacterium with broad spectrum antifungal activities.

Authors:  Ji Hye Han; In Cheon Hwang; Sung Heun Cho; Cheol Jang; Nam Gyu Kim; Seung Hun Yu; Yong Man Yu; Seung Bum Kim
Journal:  J Microbiol       Date:  2008-07-05       Impact factor: 3.422

3.  Carbon source nutrition of rapamycin biosynthesis in Streptomyces hygroscopicus.

Authors:  I Kojima; Y R Cheng; V Mohan; A L Demain
Journal:  J Ind Microbiol       Date:  1995-06
  3 in total

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