Literature DB >> 6343207

[Drug therapy of peritonitis. 6-year experience with the chemotherapeutic agent and anti-endotoxin taurolin].

G Wesch, C Petermann, M M Linder.   

Abstract

Since 1976 Taurolin is applied in clinical trials in several European states. The results being submitted show a very good activity of this substance against bacteria and endotoxin. Evaluating all clinical and experimental studies in our opinion the use of antibiotics postoperatively together with Taurolin seems to be an effective treatment of peritonitis. In our hospital taurolin has become an important part of the surgical management of severe forms of peritonitis. A development of resistant bacteria is not known up to now.

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Year:  1983        PMID： 6343207

Source DB:  PubMed          Journal:  Fortschr Med        ISSN： 0015-8178


  6 in total

Review 1.  Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review).

Authors:  Stella Baliou; Anthony M Kyriakopoulos; Demetrios A Spandidos; Vassilios Zoumpourlis
Journal:  Int J Oncol       Date:  2020-07-14       Impact factor: 5.650

2.  Oral administration of the anti-proliferative substance taurolidine has no impact on dextran sulfate sodium induced colitis-associated carcinogenesis in mice.

Authors:  Ansgar Michael Chromik; Sebastian Huss; Hayssam Osseili; Adrien Daigeler; Sabine Kersting; Dominique Sülberg; Ulrich Mittelkötter; Thomas Herdegen; Waldemar Uhl; Annette M Müller
Journal:  J Carcinog       Date:  2010-04-16

3.  [Effects and side effects of taurolin in experimental peritonitis in the rat].

Authors:  H Hart; J Seifert; W Brendel
Journal:  Langenbecks Arch Chir       Date:  1986

4.  Pharmacokinetics of taurolidine following repeated intravenous infusions measured by HPLC-ESI-MS/MS of the derivatives taurultame and taurinamide in glioblastoma patients.

Authors:  Ruediger Stendel; Louis Scheurer; Kathrin Schlatterer; Urs Stalder; Rolf W Pfirrmann; Ingo Fiss; Hanns Möhler; Laurent Bigler
Journal:  Clin Pharmacokinet       Date:  2007       Impact factor: 6.447

5.  Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia.

Authors:  Helge Frieling; Kai-Steffen Lauer; Matthias Gründling; Taras Usichenko; Konrad Meissner; Theoni Kanellopoulou; Christian Lehmann; Michael Wendt; Dragan Pavlovic
Journal:  Int J Colorectal Dis       Date:  2006-11-21       Impact factor: 2.796

Review 6.  Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (review).

Authors:  Hanns Möhler; Rolf W Pfirrmann; Karl Frei
Journal:  Int J Oncol       Date:  2014-07-28       Impact factor: 5.650
  6 in total

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