Literature DB >> 6342882

T-independent macrophage changes in murine malaria.

R Lelchuk, H M Dockrell, J H Playfair.   

Abstract

A study to investigate the participation of T cells in macrophage-mediated responses during malaria was performed in nude (nu/nu) and littermate (nu/+) mice infected with Plasmodium berghei (PB). We found that in both groups of mice spleen cells suppressed the mitogenic response to LPS. Both nu/+ and nu/nu infected mice also showed liver macrophage activation, reflected by increased plasminogen activator release. These findings suggest that at least some of the macrophage changes during malaria infection are T-independent.

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Year:  1983        PMID： 6342882      PMCID： PMC1536773     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  19 in total

1.  Lymphokine-induced secretion of plasminogen activator by murine macrophages.

Authors:  V Klimetzek; C Sorg
Journal:  Eur J Immunol       Date:  1977-03       Impact factor: 5.532

2.  Possible role of a B-cell mitogen in hypergammaglobulinaemia in malaria and trypanosomiasis.

Authors:  B M Greenwood
Journal:  Lancet       Date:  1974-03-16       Impact factor: 79.321

3.  Regulation of enzyme secretion by mononuclear phagocytes: studies with macrophage plasminogen activator and lysozyme.

Authors:  S Gordon
Journal:  Fed Proc       Date:  1978-11

4.  Secretion of plasminogen activator by human polymorphonuclear leukocytes. Modulation by glucocorticoids and other effectors.

Authors:  A Granelli-Piperno; J D Vassalli; E Reich
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307

5.  Bacille Calmette-Guérin infection in the mouse. Regulation of macrophage plasminogen activator by T lymphocytes and specific antigen.

Authors:  S Gordon; Z A Cohn
Journal:  J Exp Med       Date:  1978-04-01       Impact factor: 14.307

6.  Splenomegaly, enhanced phagocytosis, and anemia are thymus-dependent responses to malaria.

Authors:  D W Roberts; W P Weidanz
Journal:  Infect Immun       Date:  1978-06       Impact factor: 3.441

7.  Differential sensitivity in vivo of lethal and nonlethal malarial parasites to endotoxin-induced serum factor.

Authors:  J Taverne; P Depledge; J H Playfair
Journal:  Infect Immun       Date:  1982-09       Impact factor: 3.441

8.  Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.

Authors:  P J Fraker; J C Speck
Journal:  Biochem Biophys Res Commun       Date:  1978-02-28       Impact factor: 3.575

9.  Immunity to Plasmodium Berghei yoelii in mice. I. The course of infection in T cell and B cell deficient mice.

Authors:  F I Weinbaum; C B Evans; R E Tigelaar
Journal:  J Immunol       Date:  1976-11       Impact factor: 5.422

10.  Macrophage plasminogen activator: induction by products of activated lymphoid cells.

Authors:  J D Vassalli; E Reich
Journal:  J Exp Med       Date:  1977-02-01       Impact factor: 14.307
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  3 in total

1.  Oxygen radical release by adherent cell populations during the initial stages of a lethal rodent malarial infection.

Authors:  A O Wozencraft; S L Croft; G Sayers
Journal:  Immunology       Date:  1985-11       Impact factor: 7.397

2.  Role of macrophages in malaria: O2 metabolite production and phagocytosis by splenic macrophages during lethal Plasmodium berghei and self-limiting Plasmodium yoelii infection in mice.

Authors:  V Brinkmann; S H Kaufmann; M M Simon; H Fischer
Journal:  Infect Immun       Date:  1984-06       Impact factor: 3.441

3.  Macrophage cytotoxicity in lethal and non-lethal murine malaria and the effect of vaccination.

Authors:  J Taverne; J D Treagust; J H Playfair
Journal:  Clin Exp Immunol       Date:  1986-10       Impact factor: 4.330
  3 in total

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