Literature DB >> 6341890

The occurrence of serotonergic nerves in the bovine cornea.

N N Osborne.   

Abstract

Using high performance liquid chromatography (HPLC) and electrochemical detection, serotonin and its precursor 5-hydroxytryptophan (5-HTP) were identified in crude perchloric acid extracts from bovine cornea. In addition, dopamine, noradrenaline and adrenaline were identified. Through the use of immunohistochemical procedures it was established that the serotonin is localized in nerve fibers in the cornea and they were always found subepithelially or in the stroma. The occurrence of serotonergic fibres in the cornea suggests that the amine has a specific functional role in this tissue.

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Year:  1983        PMID： 6341890     DOI： 10.1016/0304-3940(83)90519-0

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  7 in total

1.  Mapping the entire nerve architecture of the cat cornea.

Authors:  Jiucheng He; Thang Luong Pham; Haydee E P Bazan
Journal:  Vet Ophthalmol       Date:  2019-01-30       Impact factor: 1.644

2.  Selective serotonin reuptake inhibitors: a review of its effects on intraocular pressure.

Authors:  Ciro Costagliola; Francesco Parmeggiani; Francesco Semeraro; Adolfo Sebastiani
Journal:  Curr Neuropharmacol       Date:  2008-12       Impact factor: 7.363

3.  Effect of topical ketanserin administration on intraocular pressure.

Authors:  C Costagliola; G Iuliano; M Rinaldi; V Russo; G Scibelli; L Mastropasqua
Journal:  Br J Ophthalmol       Date:  1993-06       Impact factor: 4.638

Review 4.  SSRIs and intraocular pressure modifications: evidence, therapeutic implications and possible mechanisms.

Authors:  Ciro Costagliola; Francesco Parmeggiani; Adolfo Sebastiani
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

5.  Effects of topical timolol (0.5%) and betaxolol (0.5%) on corneal sensitivity.

Authors:  S S Weissman; P A Asbell
Journal:  Br J Ophthalmol       Date:  1990-07       Impact factor: 4.638

6.  Biochemical and immunohistochemical determination of 5-hydroxytryptamine located in mast cells in the trigeminal ganglion of the rat and guinea pig.

Authors:  J I Lehtosalo; H Uusitalo; J Laakso; A Palkama; M Härkönen
Journal:  Histochemistry       Date:  1984

Review 7.  Immunomodulatory Role of Neuropeptides in the Cornea.

Authors:  Sudan Puri; Brendan M Kenyon; Pedram Hamrah
Journal:  Biomedicines       Date:  2022-08-16
  7 in total

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