Literature DB >> 6341255

Correlation between low levels of maternal IgG antibodies to R protein and neonatal septicemia with group B streptococci carrying R protein.

V Lindén, K K Christensen, P Christensen.   

Abstract

A method was designed for quantitation of serum antibodies to R protein in group B streptococci (GBS). Four sera from mothers of infants with neonatal septicemia caused by type II, R+ GBS showed a binding range from 400 to 740 cpm in contrast to a range of 690-1,220 cpm in 5 parturients carrying type II, R+ strains in the urogenital tract giving birth to healthy infants (p less than 0.05). The range of antibodies in sera from 8 mothers to infants infected with GBS type III,R+ was 370-750 cpm, whereas the range in sera from 10 carriers of type III,R+ giving birth to healthy infants varied between 510 and 1,280 cpm (p less than 0.01). These findings indicate that R protein is an important virulence factor in neonatal GBS septicemia/meningitis.

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Year:  1983        PMID： 6341255     DOI： 10.1159/000233382

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN： 0020-5915


  10 in total

1.  High expression of a C protein beta antigen gene among invasive strains from certain clonally related groups of type Ia and Ib group B streptococci.

Authors:  Noriyuki Nagano; Yukiko Nagano; Fumiaki Taguchi
Journal:  Infect Immun       Date:  2002-08       Impact factor: 3.441

2.  Properties of group B streptococci with protein surface antigens X and R.

Authors:  I W Wibawan; C Lämmler
Journal:  J Clin Microbiol       Date:  1990-12       Impact factor: 5.948

3.  Association between low concentrations of antibodies to protein alpha and Rib and invasive neonatal group B streptococcal infection.

Authors:  C Larsson; M Lindroth; P Nordin; M Stålhammar-Carlemalm; G Lindahl; I Krantz
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2006-11       Impact factor: 5.747

4.  Molecular species of R-protein antigens produced by clinical isolates of group B streptococci.

Authors:  A E Flores; P Ferrieri
Journal:  J Clin Microbiol       Date:  1989-05       Impact factor: 5.948

5.  A protective surface protein from type V group B streptococci shares N-terminal sequence homology with the alpha C protein.

Authors:  C S Lachenauer; L C Madoff
Journal:  Infect Immun       Date:  1996-10       Impact factor: 3.441

6.  Antibodies against Streptococcus agalactiae proteins c(alpha) and R4 in sera from pregnant women from Norway and Zimbabwe.

Authors:  S R Moyo; J A Maeland; J Mudzori
Journal:  Clin Diagn Lab Immunol       Date:  2001-11

7.  Molecular analysis of group B protective surface protein, a new cell surface protective antigen of group B streptococci.

Authors:  Sezgin Erdogan; Peter K Fagan; Susanne R Talay; Manfred Rohde; Patricia Ferrieri; Aurea E Flores; Carlos A Guzmán; Mark J Walker; Gursharan S Chhatwal
Journal:  Infect Immun       Date:  2002-02       Impact factor: 3.441

8.  Immune responses to the R4 protein antigen of group B streptococci and its relationship to other streptococcal R4 proteins.

Authors:  E L Fasola; A E Flores; P Ferrieri
Journal:  Clin Diagn Lab Immunol       Date:  1996-05

9.  Maternal immunization of mice with group B streptococcal type III polysaccharide-beta C protein conjugate elicits protective antibody to multiple serotypes.

Authors:  L C Madoff; L C Paoletti; J Y Tai; D L Kasper
Journal:  J Clin Invest       Date:  1994-07       Impact factor: 14.808

10.  Intravenous administration of human IgG to newborn infants: changes in serum antibody levels to group B streptococci.

Authors:  K K Christensen; P Christensen; H U Bucher; G Duc; C H Kind; D Mieth; B Müller; R A Seger
Journal:  Eur J Pediatr       Date:  1984-12       Impact factor: 3.183
  10 in total

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