Literature DB >> 6340670

Photoaffinity inhibition of peptide transport in yeast.

P Sarthou, M Gonneau, F Le Goffic.   

Abstract

A photoaffinity label, 4-azidobenzoyltrimethionine has been synthesized. It competitively inhibits trimethionine uptake in the yeast C. albicans. Upon UV irradiation it irreversibly and specifically blocks oligopeptide uptake. These results give the first example of photoinhibition of peptide uptake in yeast.

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Year:  1983        PMID: 6340670     DOI: 10.1016/0006-291x(83)91044-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  2 in total

1.  Sensitivity to nikkomycin Z in Candida albicans: role of peptide permeases.

Authors:  J C Yadan; M Gonneau; P Sarthou; F Le Goffic
Journal:  J Bacteriol       Date:  1984-12       Impact factor: 3.490

2.  Mechanism of action of anticandidal dipeptides containing inhibitors of glucosamine-6-phosphate synthase.

Authors:  S Milewski; R Andruszkiewicz; L Kasprzak; J Mazerski; F Mignini; E Borowski
Journal:  Antimicrob Agents Chemother       Date:  1991-01       Impact factor: 5.191

  2 in total

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