Literature DB >> 6340538

Combined chloroquine/Fansidar-resistant falciparum malaria appears in East Africa.

U Hess, P M Timmermans, M Jones.   

Abstract

The first two cases from East Africa of RII chloroquine- and Fansidar-resistant falciparum malaria are described. The first case occurred in a non-immune Swedish expatriate 2 weeks after arrival in Tanzania, and the second in a semi-immune Tanzanian soldier. Fansidar has not yet been marketed in Tanzania. The significance and etiology of the occurrence of combined chloroquine/Fansidar resistance in East Africa are discussed.

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Year:  1983        PMID： 6340538     DOI： 10.4269/ajtmh.1983.32.217

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  6 in total

1.  Development of an in vitro microtest for determining the susceptibility of Plasmodium falciparum to sulfadoxine-pyrimethamine: laboratory investigations and field studies in Port-au-Prince, Haiti.

Authors:  P Nguyen-Dinh; D Payne; A Teklehaimanot; A Zevallos-Ipenza; M M Day; Y T Duverseau
Journal:  Bull World Health Organ       Date:  1985       Impact factor: 9.408

2.  Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.

Authors:  Carolyn K Dong; Vishal Patel; Jimmy C Yang; Jeffrey D Dvorin; Manoj T Duraisingh; Jon Clardy; Dyann F Wirth
Journal:  Bioorg Med Chem Lett       Date:  2008-11-24       Impact factor: 2.823

3.  Activity of a combination of three cinchona bark alkaloids against Plasmodium falciparum in vitro.

Authors:  P Druilhe; O Brandicourt; T Chongsuphajaisiddhi; J Berthe
Journal:  Antimicrob Agents Chemother       Date:  1988-02       Impact factor: 5.191

4.  Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.

Authors:  Vishal Patel; Michael Booker; Martin Kramer; Leila Ross; Cassandra A Celatka; Leah M Kennedy; Jeffrey D Dvorin; Manoj T Duraisingh; Piotr Sliz; Dyann F Wirth; Jon Clardy
Journal:  J Biol Chem       Date:  2008-10-08       Impact factor: 5.157

5.  Prospective double-blind trial of two different doses of mefloquine plus pyrimethamine-sulfadoxine compared with pyrimethamine-sulfadoxine alone in the treatment of falciparum malaria.

Authors:  D Botero; M Restrepo; A Montoya
Journal:  Bull World Health Organ       Date:  1985       Impact factor: 9.408

6.  Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.

Authors:  Vishal Patel; Ralph Mazitschek; Bradley Coleman; Cokey Nguyen; Sameer Urgaonkar; Joseph Cortese; Robert H Barker; Edward Greenberg; Weiping Tang; James E Bradner; Stuart L Schreiber; Manoj T Duraisingh; Dyann F Wirth; Jon Clardy
Journal:  J Med Chem       Date:  2009-04-23       Impact factor: 7.446
  6 in total

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