Literature DB >> 6339554

Multidose vials versus single-dose vials: a study in sterility and cost-effectiveness.

N K Sheth, G T Post, T R Wisniewski, B V Uttech.   

Abstract

A total of 197 multidose injectable vials were collected from 10 different nursing stations and evaluated for sterility. Experimental contamination studies were undertaken, and the cost-effectiveness of multidose vials was compared with that of single-dose vials. Our results showed that bacterial contamination of multidose injectable vials was not a significant hazard; in addition, contrary to common belief, the use of multidose vials was not always successful as a cost-containment measure.

Mesh：

Year:  1983        PMID： 6339554      PMCID： PMC272643          DOI： 10.1128/jcm.17.2.377-379.1983

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  9 in total

1.  POTENTIAL HEALTH HAZARDS IN THE MULTIPLE-DOSE VIAL.

Authors:  A L ROSENZWEIG
Journal:  Hospitals       Date:  1964-06-16

2.  Sterility of multiple dose vials after repeated use.

Authors:  J A YOUNG; T S COLLETTE; W F BREHM
Journal:  Am Surg       Date:  1958-11       Impact factor: 0.688

3.  A study of contamination of multiple-dose medication vials.

Authors:  S KOHAN; H CARLIN; R WHITEHEAD
Journal:  Hospitals       Date:  1962-07-16

4.  Bacterial killing by bacteriostatic saline solutions--potential for diagnostic error.

Authors:  M F Rein; G L Mandell
Journal:  N Engl J Med       Date:  1973-10-11       Impact factor: 91.245

5.  Study shows contamination in multiple-dose vials.

Authors:  J Bothe
Journal:  AORN J       Date:  1973-05       Impact factor: 0.676

6.  The sterility of multiple-dose vials in challenged.

Authors:  J F Ridgway; W K McAuliff
Journal:  Hosp Manage       Date:  1967-07

7.  Multiple dose vials: a source of contamination?

Authors:  C E Corley; J P Manos; J D Thomas
Journal:  J S C Med Assoc       Date:  1968-11

8.  Studies on in-use microbial contamination of multiple-dose vials.

Authors:  O T Olson; B Aslund; E Sandell
Journal:  Acta Pharm Suec       Date:  1978

9.  Growth of nosocomial pathogens in multiple-dose parenteral medication vials.

Authors:  A K Highsmith; G P Greenhood; J R Allen
Journal:  J Clin Microbiol       Date:  1982-06       Impact factor: 5.948
  9 in total
  6 in total

Review 1.  Controversies in hospital infection control.

Authors:  F D Daschner; U Frank
Journal:  Eur J Clin Microbiol       Date:  1987-06       Impact factor: 3.267

2.  Contamination of multiple-dose vials due to repeat use of syringes.

Authors: 
Journal:  CMAJ       Date:  1989-03-01       Impact factor: 8.262

3.  Practical infection control.

Authors:  A J Berry
Journal:  Can J Anaesth       Date:  1995-11       Impact factor: 5.063

4.  Single versus multi-dose vaccine vials: an economic computational model.

Authors:  Bruce Y Lee; Bryan A Norman; Tina-Marie Assi; Sheng-I Chen; Rachel R Bailey; Jayant Rajgopal; Shawn T Brown; Ann E Wiringa; Donald S Burke
Journal:  Vaccine       Date:  2010-06-03       Impact factor: 3.641

5.  Survival of Serratia marcescens in benzalkonium chloride and in multiple-dose medication vials: relationship to epidemic septic arthritis.

Authors:  A K Nakashima; A K Highsmith; W J Martone
Journal:  J Clin Microbiol       Date:  1987-06       Impact factor: 5.948

6.  Intravitreal administration of bevacizumab: pros and cons.

Authors:  Simin Dashti-Khavidaki; Mohammad Abdollahi
Journal:  Daru       Date:  2015-04-21       Impact factor: 3.117
  6 in total

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