Literature DB >> 6339415

In vitro activity of ceftazidime (GR 20263) and other beta-lactam antibiotics against Haemophilus influenzae.

P Piot, E Van Dyck, J Colaert.   

Abstract

Minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) were determined for ceftazidime (GR 20263 - pentahydrate), RO 13-9904, cefoperazone, cefotaxime, lamoxactam, cefamandole and ampicillin using clinical isolates of beta-lactamase-producing and beta-lactamase-negative Haemophilus influenzae. RO 13-9904 and cefotaxime were the most active, followed by ceftazidime, lamoxactam and cefoperazone. Ceftazidime displayed high stability against the beta-lactamase-producing strains with a low MBC:MIC ratio.

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Year:  1983        PMID： 6339415     DOI： 10.1007/bf01641103

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  9 in total

1.  Concentrations of bacteria in cerebrospinal fluid of patients with bacterial meningitis.

Authors:  W E Feldman
Journal:  J Pediatr       Date:  1976-04       Impact factor: 4.406

2.  [Drug sensitivity of Haemophilus sp. and transfer of resistance into E. coli (author's transl)].

Authors:  F W Goldstein; A Boisivon; P Leclerc; J F Acar
Journal:  Pathol Biol (Paris)       Date:  1977-05

3.  Ampicillin-resistant Haemophilus influenzae type B infection.

Authors:  M O Tomeh; S E Starr; J E McGowan; P M Terry; A J Nahmias
Journal:  JAMA       Date:  1974-07-15       Impact factor: 56.272

4.  Haemophilus influenzae type B resistant to ampicillin. A report of two cases.

Authors:  W Khan; S Ross; W Rodriguez; G Controni; A K Saz
Journal:  JAMA       Date:  1974-07-15       Impact factor: 56.272

5.  Ro 13-9904: A cephalosporin with a high degree of activity and broad antibacterial activity: an invitro comparative study.

Authors:  R Wise; A P Gillett; J M Andrews; K A Bedford
Journal:  J Antimicrob Chemother       Date:  1980-09       Impact factor: 5.790

6.  In vitro antimicrobial activity of cefoperazone, cefotaxime, moxalactam (LY127935), azlocillin, mezlocillin, and other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase-producing strains.

Authors:  C N Baker; C Thornsberry; R N Jones
Journal:  Antimicrob Agents Chemother       Date:  1980-04       Impact factor: 5.191

7.  Effect of inoculum size and beta-lactamase production on in vitro activity of new cephalosporins against Haemophilus species.

Authors:  R R Bulger; J A Washington
Journal:  Antimicrob Agents Chemother       Date:  1980-03       Impact factor: 5.191

8.  GR 20263, a new broad-spectrum cephalosporin with anti-pseudomonal activity.

Authors:  C H O'Callaghan; P Acred; P B Harper; D M Ryan; S M Kirby; S M Harding
Journal:  Antimicrob Agents Chemother       Date:  1980-05       Impact factor: 5.191

9.  GR-20263: a new aminothiazolyl cephalosporin with high activity against Pseudomonas and Enterobacteriaceae.

Authors:  L Verbist; J Verhaegen
Journal:  Antimicrob Agents Chemother       Date:  1980-05       Impact factor: 5.191
  9 in total
  2 in total

1.  In vitro activity of second and third generation cephalosporins against ampicillin susceptible and resistant haemophilus influenzae.

Authors:  J L Burns; K Wong; A L Smith
Journal:  Infection       Date:  1988 Sep-Oct       Impact factor: 3.553

Review 2.  Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  D M Richards; R N Brogden
Journal:  Drugs       Date:  1985-02       Impact factor: 9.546
  2 in total

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