| Literature DB >> 6339276 |
M Deleers, P Lebrun, W J Malaisse.
Abstract
When rat islets are preincubated with fluorescein diacetate and examined in a spectrofluorometer, the intracellular pH rapidly increases by 0.21 pH units in response to a rise from 1.7-16.8 mM glucose. This coincides with a marked increase in 14CO3H- net uptake by the islets, suggesting that the glucose-induced increase in H+ generation rate is compensated for by stimulation of CO3H-/Cl- exchange.Entities:
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Year: 1983 PMID： 6339276 DOI： 10.1016/0014-5793(83)80882-5
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124