| Literature DB >> 6339265 |
Abstract
One difficulty in the production of allophenic mice by aggregation of preimplantation embryos is that they frequently roll apart before the bonds between the blastomeres have had time to form. One solution to the problem, described here, is to pretreat one of the embryos with rabbit anti-mouse serum just prior to pushing them together. Blastocyst formation is unhampered by antibody treatment, and numerous allophenic mice have already been produced with this new procedure.Entities:
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Year: 1983 PMID: 6339265 DOI: 10.1007/bf01958897
Source DB: PubMed Journal: Experientia ISSN: 0014-4754