| Literature DB >> 6338566 |
L A Fisher, G Jessen, M R Brown.
Abstract
The efferent mechanisms by which central administration of corticotropin-releasing factor (CRF) elevates mean arterial pressure and heart rate were assessed in unanesthetized, unrestrained rats. CRF increased blood pressure and heart rate by stimulating noradrenergic sympathetic nervous outflow. CRF-induced cardiovascular changes were not dependent on anterior pituitary hormone release, adrenomedullary epinephrine secretion, the renin-angiotensin system or circulating vasopressin.Entities:
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Year: 1983 PMID: 6338566 DOI: 10.1016/0167-0115(83)90123-4
Source DB: PubMed Journal: Regul Pept ISSN: 0167-0115