Literature DB >> 6337722

Rat myoblast fusion requires metalloendoprotease activity.

C B Couch, W J Strittmatter.   

Abstract

The calcium-dependent fusion of cultured rat myoblasts to multinucleate myotubes appears to require the activity of a neutral metalloendoprotease at the time of fusion. Metalloendoprotease inhibitors and synthetic dipeptide substrates prevent myoblast fusion when added to fusion-competent myoblasts with the addition of calcium. Metalloendoprotease activity has been identified and partially characterized in myoblast membranes with a fluorogenic protease substrate, and is inhibited by the same compounds that prevent fusion.

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Year:  1983        PMID： 6337722     DOI： 10.1016/0092-8674(83)90516-0

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  27 in total

1.  Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates myogenesis and beta1 integrin expression in vitro.

Authors:  Gentian Lluri; Garret D Langlois; Paul D Soloway; Diane M Jaworski
Journal:  Exp Cell Res       Date:  2007-06-27       Impact factor: 3.905

2.  Regulation of TIMP-2, MT1-MMP, and MMP-2 expression during C2C12 differentiation.

Authors:  Gentian Lluri; Diane M Jaworski
Journal:  Muscle Nerve       Date:  2005-10       Impact factor: 3.217

3.  Muscle CD31(-) CD45(-) side population cells promote muscle regeneration by stimulating proliferation and migration of myoblasts.

Authors:  Norio Motohashi; Akiyoshi Uezumi; Erica Yada; So-ichiro Fukada; Kazuhiro Fukushima; Kazuhiko Imaizumi; Yuko Miyagoe-Suzuki; Shin'ichi Takeda
Journal:  Am J Pathol       Date:  2008-07-31       Impact factor: 4.307

4.  Characterization of fusion from without induced by herpes simplex virus.

Authors:  I Walev; K C Wollert; K Weise; D Falke
Journal:  Arch Virol       Date:  1991       Impact factor: 2.574

5.  Isolation and characterization of a variant myoblast cell line that is temperature sensitive for differentiation.

Authors:  R J Akhurst; N B Flavin; J Worden
Journal:  Mol Cell Biol       Date:  1988-06       Impact factor: 4.272

6.  Urokinase-dependent adhesion loss and shape change after cyclic adenosine monophosphate elevation in cultured rat mesangial cells.

Authors:  W F Glass; R A Radnik; J A Garoni; J I Kreisberg
Journal:  J Clin Invest       Date:  1988-12       Impact factor: 14.808

Review 7.  The fusion of myoblasts.

Authors:  M J Wakelam
Journal:  Biochem J       Date:  1985-05-15       Impact factor: 3.857

8.  Correlation between fusion and the developmental regulation of membrane glycoproteins in L6 myoblasts.

Authors:  J Rosenberg; A Szabo; D Rheuark; C Kayalar
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

9.  Metalloendoprotease inhibitors that block fusion also prevent biochemical differentiation in L6 myoblasts.

Authors:  E Baldwin; C Kayalar
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

10.  Proteolysis of ankyrin and of band 3 protein in chemically induced cell fusion. Ca2+ is not mandatory for fusion.

Authors:  R D Lang; C Wickenden; J Wynne; J A Lucy
Journal:  Biochem J       Date:  1984-03-01       Impact factor: 3.857
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