Literature DB >> 6335495

Glutathione depletion enhances the lifetime of oxygen-reactive radicals in mammalian cells.

R J Hodgkiss, N R Jones, M E Watts, M Woodcock.   

Abstract

When the cellular glutathione content is reduced, adding oxygen (130 mumol dm-3) 7 ms after irradiation of hypoxic cells increases the radiosensitivity (factor approximately 1.25), whereas it has much less effect in normal cells.

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Year:  1984        PMID: 6335495     DOI: 10.1080/09553008414551901

Source DB:  PubMed          Journal:  Int J Radiat Biol Relat Stud Phys Chem Med        ISSN: 0020-7616


  2 in total

1.  Free radical injury to irradiated cells: evidence from rapid irradiation studies.

Authors:  B D Michael
Journal:  Br J Cancer Suppl       Date:  1987-06

Review 2.  Iron, radiation, and cancer.

Authors:  R G Stevens; D R Kalkwarf
Journal:  Environ Health Perspect       Date:  1990-07       Impact factor: 9.031

  2 in total

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