Literature DB >> 6335236

The effect of anti-malarial drugs on human natural killer cells in vitro.

A Ferrante, D H Goh.   

Abstract

Human natural killer (NK) cell cytotoxicity against K-562 target was found to be markedly depressed by quinacrine, mefloquine, pyrimethamine and chloroquine. The most potent were quinacrine and mefloquine. Two other drugs tested, quinine and primaquine, displayed no significant effects even after long incubation periods with effector cells. The results showed that the inhibitory effects were not related to an inhibition of effector cell binding to target or to a toxic effect on NK cells.

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Year:  1984        PMID： 6335236     DOI： 10.1111/j.1365-3024.1984.tb00826.x

Source DB:  PubMed          Journal:  Parasite Immunol        ISSN： 0141-9838            Impact factor:   2.280


  7 in total

1.  Depression of human polymorphonuclear leucocyte function by anti-malarial drugs.

Authors:  A Ferrante; B Rowan-Kelly; W K Seow; Y H Thong
Journal:  Immunology       Date:  1986-05       Impact factor: 7.397

2.  Elevated natural killer (NK) cytotoxicity of mononuclear leucocytes from splenectomized patients: increase in Leu-7+ and Leu-11+ leucocytes.

Authors:  A Ferrante; G K Kiroff; P A Drew
Journal:  Clin Exp Immunol       Date:  1986-04       Impact factor: 4.330

3.  Multispecific targeting of glioblastoma with tumor microenvironment-responsive multifunctional engineered NK cells.

Authors:  Jiao Wang; Sandra Toregrosa-Allen; Bennett D Elzey; Sagar Utturkar; Nadia Atallah Lanman; Victor Bernal-Crespo; Matthew M Behymer; Gregory T Knipp; Yeonhee Yun; Michael C Veronesi; Anthony L Sinn; Karen E Pollok; Randy R Brutkiewicz; Kathryn S Nevel; Sandro Matosevic
Journal:  Proc Natl Acad Sci U S A       Date:  2021-11-09       Impact factor: 12.779

4.  Effects of amodiaquine, chloroquine, and mefloquine on human polymorphonuclear neutrophil function in vitro.

Authors:  M T Labro; C Babin-Chevaye
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

5.  Conditioned medium from stimulated mononuclear leukocytes augments human neutrophil-mediated killing of a virulent Acanthamoeba sp.

Authors:  A Ferrante; T J Abell
Journal:  Infect Immun       Date:  1986-02       Impact factor: 3.441

6.  Evaluation of antimalarial activity and toxicity of a new primaquine prodrug.

Authors:  Marcelo Gomes Davanço; Anna Caroline Campos Aguiar; Leandro Alves Dos Santos; Elias Carvalho Padilha; Michel Leandro Campos; Cleverton Roberto de Andrade; Luiz Marcos da Fonseca; Jean Leandro Dos Santos; Chung Man Chin; Antoniana Ursine Krettli; Rosangela Gonçalves Peccinini
Journal:  PLoS One       Date:  2014-08-18       Impact factor: 3.240

7.  Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro.

Authors:  Amandine Pradier; Maria Papaserafeim; Ning Li; Anke Rietveld; Charlotte Kaestel; Lyssia Gruaz; Cédric Vonarburg; Rolf Spirig; Gisella L Puga Yung; Jörg D Seebach
Journal:  Front Immunol       Date:  2019-03-27       Impact factor: 7.561
  7 in total

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