Literature DB >> 6334363

Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.

D F Wong, H N Wagner, R F Dannals, J M Links, J J Frost, H T Ravert, A A Wilson, A E Rosenbaum, A Gjedde, K H Douglass.   

Abstract

D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human subjects by positron emission tomography after intravenous injection of 11C-labeled 3-N-methylspiperone. Levels of receptor in the caudate nucleus, putamen, and frontal cerebral cortex declined over the age span studied (19 to 73 years). The decline in D2 receptor in males was different from that in females.

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Year:  1984        PMID： 6334363     DOI： 10.1126/science.6334363

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  95 in total

Review 1.  Behavioural problems associated with dementia: the role of newer antipsychotics.

Authors:  G Stoppe; C A Brandt; J H Staedt
Journal:  Drugs Aging       Date:  1999-01       Impact factor: 3.923

2.  Positron emission tomography experience with 2-[¹⁸F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-[¹⁸F]FA) in the living human brain of smokers with paranoid schizophrenia.

Authors:  James Robert Brašić; Nicola Cascella; Anil Kumar; Yun Zhou; John Hilton; Vanessa Raymont; Andrew Crabb; Maria Rita Guevara; Andrew G Horti; Dean Foster Wong
Journal:  Synapse       Date:  2011-12-29       Impact factor: 2.562

3.  Masahiro Iio Memorial Lecture.

Authors:  H N Wagner
Journal:  Ann Nucl Med       Date:  1992-02       Impact factor: 2.668

Review 4.  Cognitive decline and aging: the role of concussive and subconcussive impacts.

Authors:  Steven P Broglio; James T Eckner; Henry L Paulson; Jeffery S Kutcher
Journal:  Exerc Sport Sci Rev       Date:  2012-07       Impact factor: 6.230

Review 5.  Pharmacological implications for neuroreceptor imaging.

Authors:  N P Verhoeff
Journal:  Eur J Nucl Med       Date:  1991

6.  Age-related changes in human D1 dopamine receptors measured by positron emission tomography.

Authors:  T Suhara; H Fukuda; O Inoue; T Itoh; K Suzuki; T Yamasaki; Y Tateno
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

Review 7.  Intersection between metabolic dysfunction, high fat diet consumption, and brain aging.

Authors:  Romina M Uranga; Annadora J Bruce-Keller; Christopher D Morrison; Sun Ok Fernandez-Kim; Philip J Ebenezer; Le Zhang; Kalavathi Dasuri; Jeffrey N Keller
Journal:  J Neurochem       Date:  2010-05-06       Impact factor: 5.372

8.  Dopamine-dependent cognitive processes after menopause: the relationship between COMT genotype, estradiol, and working memory.

Authors:  Julie A Dumas; Jenna A Makarewicz; Janice Bunn; Joshua Nickerson; Elizabeth McGee
Journal:  Neurobiol Aging       Date:  2018-08-16       Impact factor: 4.673

9.  Is getting older all that rewarding?

Authors:  Dean F Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-23       Impact factor: 11.205

10.  Age-related changes of gene expression in the neocortex: preliminary data on RNA-Seq of the transcriptome in three functionally distinct cortical areas.

Authors:  Oksana Yu Naumova; Dean Palejev; Natalia V Vlasova; Maria Lee; Sergei Yu Rychkov; Olga N Babich; Flora M Vaccarino; Elena L Grigorenko
Journal:  Dev Psychopathol       Date:  2012-11
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