Literature DB >> 63343

The effects of BCG on both cellular and humoral immunity during the early response to a hapten carrier complex.

P J Neveu.   

Abstract

Cell-mediated reactions to the carrier and antibody-mediated reactions to hapten and carrier were studied in guinea-pigs treated with a single i.v. injection of BCG at different intervals of time before immunization with two different doses of a hapten-carrier complex. The results clearly show that BCG-induced delayed hypersensitivity reactions to the carrier and decreased antibody synthesis to the hapten. It is proposed that BCG acts on a dispatcher cell which controls both cellular and humoral immunity.

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Year:  1976        PMID： 63343      PMCID： PMC1540825     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  14 in total

1.  Activation of lymphoid cells by BCG in vitro.

Authors:  M B Mokyr; M S Mitchell
Journal:  Cell Immunol       Date:  1975-02       Impact factor: 4.868

2.  Immunopotentiation with BCG. II. Modulation of the response to sheep red blood cells.

Authors:  T E Miller; G B Mackaness; P H Lagrange
Journal:  J Natl Cancer Inst       Date:  1973-11       Impact factor: 13.506

3.  Separation of T effector cells in humoral and cellular immunity.

Authors:  B E Elliot; J S Haskill
Journal:  Nature       Date:  1974-12-13       Impact factor: 49.962

4.  Enhancement of renal allografts in rats and man.

Authors:  M E French; J R Batchelor
Journal:  Transplant Rev       Date:  1972

5.  Modulation of the immune response of guinea pigs by repeated BCG scarification.

Authors:  L C Peters; M G Hanna; J V Gutterman; G M Mavligit; E M Hersh
Journal:  Proc Soc Exp Biol Med       Date:  1974-11

6.  Carrier function in immune deviation.

Authors:  P J Neveu; A G Borduas
Journal:  J Immunol       Date:  1974-03       Impact factor: 5.422

7.  Dissociation of T cell helper function and delayed hypersensitivity.

Authors:  J Silver; B Benacerraf
Journal:  J Immunol       Date:  1974-12       Impact factor: 5.422

8.  A bicellular mechanism in the immune response to chemically defined antigens. I. Antibody formation in vitro.

Authors:  S Segal; A Globerson; M Feldman
Journal:  Cell Immunol       Date:  1971-06       Impact factor: 4.868

9.  Cell-mediated immunity and serum blocking factors in patients with chronic dermatophytic infections.

Authors:  B A Walters; J E Chick; W J Halliday
Journal:  Int Arch Allergy Appl Immunol       Date:  1974

Review 10.  Specific fractionation of immunocompetent cells.

Authors:  H Wigzell
Journal:  Transplant Rev       Date:  1970
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  2 in total

1.  The effects of thiol moiety of levamisole on both cellular and humoral immunity during the early response to a hapten-carrier complex.

Authors:  P J Neveu
Journal:  Clin Exp Immunol       Date:  1978-06       Impact factor: 4.330

2.  Stimulation and inhibition of macrophages prior to immunization with a hapten-carrier conjugate.

Authors:  P J Neveu
Journal:  Immunology       Date:  1977-08       Impact factor: 7.397
  2 in total

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