Literature DB >> 6334072

A metronidazole-resistant strain of Trichomonas vaginalis and its sensitivity to Go 10213.

D K Ray, J S Tendulkar, V B Shrivastava, A K Datta, K Nagarajan.   

Abstract

In the present study the comparative in-vitro and in-vivo efficacy of Go 10213 was compared with those of metronidazole, secnidazole, tinidazole, ornidazole and nimorazole against a metronidazole-resistant strain of T. vaginalis. Go 10213 was found to be superior in activity. It appears more promising than the drugs mentioned above on the basis of the evidence presented.

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Year:  1984        PMID: 6334072     DOI: 10.1093/jac/14.4.423

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  3 in total

1.  Anti-Trichomonas vaginalis monoclonal antibodies inducing complement-dependent cytotoxicity.

Authors:  N Moav; E Draghi; A David; D Gold
Journal:  Immunology       Date:  1988-01       Impact factor: 7.397

2.  Antibacterial activity of GO 10213, a nitroimidazole derivative.

Authors:  H Hof; J Ströder
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

Review 3.  Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis.

Authors:  J C Gillis; L R Wiseman
Journal:  Drugs       Date:  1996-04       Impact factor: 9.546

  3 in total

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