Literature DB >> 6333293

Recent developments in the treatment of onchocerciasis.

H R Taylor.   

Abstract

The treatment of onchocerciasis using diethylcarbamazine and suramin sodium, which can kill different stages of the parasite, Onchocerca volvulus, remains unsatisfactory. Recent studies have more clearly defined the serious limitations of the existing forms of treatment. However, two new classes of compounds, the benzimidazoles and avermectins, offer exciting new leads in the search for a safe and effective treatment that could be used on a large scale.

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Year:  1984        PMID： 6333293      PMCID： PMC2536340     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN： 0042-9686            Impact factor:   9.408


  37 in total

1.  Letter: Further trial of levamisole against Onchocerca volvulus.

Authors:  B O Duke
Journal:  Trans R Soc Trop Med Hyg       Date:  1975       Impact factor: 2.184

2.  Effect of mebendazole and levamisole on Onchocerca volvulus and Dipetalonema perstans.

Authors:  K Maertens; M Wéry
Journal:  Trans R Soc Trop Med Hyg       Date:  1975       Impact factor: 2.184

3.  Trial of thiabendazole for the treatment of onchocerciasis.

Authors:  B O Duke; F Hawking
Journal:  Trans R Soc Trop Med Hyg       Date:  1967       Impact factor: 2.184

4.  Onchocerciasis: invasion of deep organs by Onchocerca volvulus.

Authors:  W M Meyers; R C Neafie; D H Connor
Journal:  Am J Trop Med Hyg       Date:  1977-07       Impact factor: 2.345

5.  Long-term treatment of onchocerciasis in children with low doses of diethylcarbamazine.

Authors:  J Sowa; S C Sowa
Journal:  Ann Trop Med Parasitol       Date:  1978-02

6.  Mebendazole in enterobiasis. Radiochemical and pilot clinical study in 1,278 subjects.

Authors:  J P Brugmans; D C Thienpont; I van Wijngaarden; O F Vanparijs; V L Schuermans; H L Lauwers
Journal:  JAMA       Date:  1971-07-19       Impact factor: 56.272

7.  Effects of a single dose of metrifonate on the forest strain of Onchocerca volvulus in Cameroon.

Authors:  H Fuglsang; J Anderson
Journal:  Tropenmed Parasitol       Date:  1977-12

8.  The effects of drugs on Onchocerca volvulus. 1. Methods of assessment, population dynamics of the parasite and the effects of diethylcarbamazine.

Authors:  B O Duke
Journal:  Bull World Health Organ       Date:  1968       Impact factor: 9.408

9.  Effects of suramin on ocular onchocerciasis.

Authors:  J Anderson; H Fuglsang; T F de C Marshall
Journal:  Tropenmed Parasitol       Date:  1976-09

10.  Effects of diethylcarbamazine on ocular onchocerciasis.

Authors:  J Anderson; H Fuglsang; T F de C Marshall
Journal:  Tropenmed Parasitol       Date:  1976-09
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  4 in total

1.  Effect of single-dose ivermectin therapy on human Onchocerca volvulus infection with onchocercal ocular involvement.

Authors:  H S Newland; A T White; B M Greene; S A D'Anna; E Keyvan-Larijani; M A Aziz; P N Williams; H R Taylor
Journal:  Br J Ophthalmol       Date:  1988-08       Impact factor: 4.638

2.  Schoolchildren and ocular onchocerciasis in the rain-forest of Cameroon.

Authors:  H C Koppert; A C Hellemans
Journal:  Doc Ophthalmol       Date:  1986-01-15       Impact factor: 2.379

Review 3.  Onchocerciasis.

Authors:  H R Taylor
Journal:  Int Ophthalmol       Date:  1990-05       Impact factor: 2.031

4.  Onchocerciasis--a potential revolution in its treatment.

Authors:  H R Taylor
Journal:  Int Ophthalmol       Date:  1987-12       Impact factor: 2.031
  4 in total

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