Literature DB >> 6332171

Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell-T cell mixtures.

D M Spalding, S I Williamson, W J Koopman, J R McGhee.   

Abstract

Polyclonal IgA secretion is inducible in murine B cells when DC-T from Peyer's patches (PP) provide the inducing stimulus. PP DC-T, which are composed predominantly of dendritic cells and Lyt-1+ T cells, are capable of dramatic augmentation of IgA secretion by PP or spleen B cells with minimal induction of IgM secretion. DC-T from spleen, however, are incapable of augmenting IgA secretion by either PP or spleen B cells. The level of IgA secretion is dependent upon the dose of DC-T providing the inducing stimulus and reaches a plateau with DC-T:B ratios of less than 1:1. This system for preferential induction of IgA responses should permit elucidation of cellular mechanisms involved in regulation of IgA secretion.

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Year:  1984        PMID： 6332171      PMCID： PMC2187398          DOI： 10.1084/jem.160.3.941

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  9 in total

1.  "Panning" for lymphocytes: a method for cell selection.

Authors:  L J Wysocki; V L Sato
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

2.  B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes.

Authors:  J F Kearney; A R Lawton
Journal:  J Immunol       Date:  1975-09       Impact factor: 5.422

3.  Characteristics and regulatory function of murine con A-induced, cloned T cells obtained from Peyer's patches and spleen: mechanisms regulating isotype-specific immunoglobulin production by Peyer's patch B cells.

Authors:  H Kawanishi; L E Saltzman; W Strober
Journal:  J Immunol       Date:  1982-08       Impact factor: 5.422

4.  An enzymatic method for preparation of dissociated murine Peyer's patch cells enriched for macrophages.

Authors:  M V Frangakis; W J Koopman; H Kiyono; S M Michalek; J R McGhee
Journal:  J Immunol Methods       Date:  1982       Impact factor: 2.303

5.  In vivo immune response to a T-cell-dependent antigen by cultures of disassociated murine Peyer's patch.

Authors:  H Kiyono; J R McGhee; M J Wannemuehler; M V Frangakis; D M Spalding; S M Michalek; W J Koopman
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

6.  Accessory cells in murine Peyer's patch. I. Identification and enrichment of a functional dendritic cell.

Authors:  D M Spalding; W J Koopman; J H Eldridge; J R McGhee; R M Steinman
Journal:  J Exp Med       Date:  1983-05-01       Impact factor: 14.307

7.  Human T cell hybridomas secreting factors for IgA-specific help, polyclonal B cell activation, and B cell proliferation.

Authors:  L Mayer; S M Fu; H G Kunkel
Journal:  J Exp Med       Date:  1982-12-01       Impact factor: 14.307

8.  Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism.

Authors:  K Inaba; A Granelli-Piperno; R M Steinman
Journal:  J Exp Med       Date:  1983-12-01       Impact factor: 14.307

9.  T-cell regulation of murine IgA synthesis.

Authors:  C O Elson; J A Heck; W Strober
Journal:  J Exp Med       Date:  1979-03-01       Impact factor: 14.307
  9 in total
  21 in total

1.  Suppression of immune response induction in Peyer's patch lymphoid cells from mice infected with mouse hepatitis virus.

Authors:  D B Casebolt; D M Spalding; T R Schoeb; J R Lindsey
Journal:  Cell Immunol       Date:  1987-10-01       Impact factor: 4.868

2.  Interleukin 12 and CD86 Regulate Th1 and Th2 Development Induced by a Range of Antigen Doses Presented by Peyer's Patch and Spleen Cells.

Authors:  Tadashi Yoshida; Satoshi Hachimura; Mina Ishimori; Wataru Ise; Mamoru Totsuka; Akio Ametani; Shuichi Kaminogawa
Journal:  Cytotechnology       Date:  2003-11       Impact factor: 2.058

3.  Detection and characterization of circulating and glomerular immune complexes in experimental IgA nephropathy.

Authors:  J González-Cabrero; J Egido; A Barat; E González
Journal:  Immunology       Date:  1990-07       Impact factor: 7.397

Review 4.  Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells.

Authors:  J Rodrigo Mora; Ulrich H von Andrian
Journal:  Semin Immunol       Date:  2008-09-18       Impact factor: 11.130

Review 5.  Dendritic cells of the gastrointestinal tract.

Authors:  B L Kelsall; W Strober
Journal:  Springer Semin Immunopathol       Date:  1997

6.  Antigen presentation by epithelial cells of the rat small intestine. I. Kinetics, antigen specificity and blocking by anti-Ia antisera.

Authors:  P W Bland; L G Warren
Journal:  Immunology       Date:  1986-05       Impact factor: 7.397

7.  Immunological responses to monoassociated Bifidobacterium longum and their relation to prevention of bacterial invasion.

Authors:  S Yamazaki; K Machii; S Tsuyuki; H Momose; T Kawashima; K Ueda
Journal:  Immunology       Date:  1985-09       Impact factor: 7.397

8.  Secretory immune responses in mouse vaginal fluid after pelvic, parenteral or vaginal immunization.

Authors:  M A Thapar; E L Parr; M B Parr
Journal:  Immunology       Date:  1990-05       Impact factor: 7.397

9.  Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node.

Authors:  Joseph M Thompson; Michael G Nicholson; Alan C Whitmore; Melodie Zamora; Ande West; Akiko Iwasaki; Herman F Staats; Robert E Johnston
Journal:  J Immunol       Date:  2008-07-01       Impact factor: 5.422

10.  Functional characteristics of the veiled cells in afferent lymph from the rat intestine.

Authors:  G Mayrhofer; P G Holt; J M Papadimitriou
Journal:  Immunology       Date:  1986-07       Impact factor: 7.397
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